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急性髓系白血病的早期眼科表现:当前观点

Early Ophthalmological Manifestations of Acute Myeloid Leukemia: Current Perspectives.

作者信息

El Salloukh Nasrine Anais, Hage Dany G, Bashshur Anna Z, Kheir Wajiha Jurdi

机构信息

Ophthalmology Department, American University of Beirut Medical Center, Beirut, Lebanon.

Tulane University School of Medicine, New Orleans, LA, USA.

出版信息

Clin Ophthalmol. 2022 Jul 1;16:2119-2127. doi: 10.2147/OPTH.S342720. eCollection 2022.

DOI:10.2147/OPTH.S342720
PMID:35800672
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9255417/
Abstract

Acute myeloid leukemia (AML) is a hematological malignancy affecting different organ systems including the eye. The purpose of this review is to present and evaluate the medical literature regarding the early ophthalmological manifestations of acute myeloid leukemia. AML affects the ocular system through direct infiltration of tissues, secondary to hematological abnormalities, or in the form of chloroma or myeloid sarcoma in the brain or orbit consequently leading to a variety of manifestations depending on the ocular tissue involved. It is imperative for ophthalmologists to be aware of the early ophthalmological manifestations of AML which will allow for earlier diagnosis and treatment of this life-threatening disease.

摘要

急性髓系白血病(AML)是一种影响包括眼睛在内的不同器官系统的血液系统恶性肿瘤。本综述的目的是呈现并评估关于急性髓系白血病早期眼科表现的医学文献。AML通过组织的直接浸润、继发于血液学异常,或以脑或眼眶中的绿色瘤或髓系肉瘤的形式影响眼部系统,从而根据受累的眼部组织导致各种表现。眼科医生必须了解AML的早期眼科表现,这将有助于对这种危及生命的疾病进行早期诊断和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/175f/9255417/5282b59c56a1/OPTH-16-2119-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/175f/9255417/7da40446bb5f/OPTH-16-2119-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/175f/9255417/5282b59c56a1/OPTH-16-2119-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/175f/9255417/7da40446bb5f/OPTH-16-2119-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/175f/9255417/5282b59c56a1/OPTH-16-2119-g0002.jpg

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Bilateral Pseudo-hypopyon as Presenting Symptom of Acute Monocytic Leukemia in an 8-Month-Old Infant.8 月龄婴儿以双侧假性前房积脓为首发表现的急性单核细胞白血病
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Emergent Radiotherapy for Leukemia-Induced Cranial Neuropathies Refractory to Intrathecal Therapy.
Hematol Rep. 2024 Mar 28;16(2):193-203. doi: 10.3390/hematolrep16020020.
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Cureus. 2021 May 24;13(5):e15212. doi: 10.7759/cureus.15212.
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Acute myeloid leukemia presenting as horizontal diplopia.以水平复视为首发表现的急性髓系白血病。
Am J Emerg Med. 2021 Nov;49:441.e1-441.e2. doi: 10.1016/j.ajem.2021.04.086. Epub 2021 May 1.
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Bilateral retinal artery occlusions as the first manifestation of extramedullary central nervous system involvement in relapsed acute myeloid leukaemia.双侧视网膜动脉阻塞作为复发性急性髓系白血病髓外中枢神经系统受累的首发表现。
BMJ Case Rep. 2021 Apr 2;14(4):e239795. doi: 10.1136/bcr-2020-239795.
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Isolated retro-orbital granulocytic sarcoma relapse of Acute Myeloid Leukemia after allogeneic hematopoietic stem cell transplantation: a case report.异基因造血干细胞移植后急性髓系白血病孤立性眶后粒细胞肉瘤复发:一例报告
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Uveal Infiltration in an Acute Myeloid Leukemia Case.急性髓系白血病病例中的葡萄膜浸润
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