Zhao Yong, Zhao Yang, Zhang Li-Qin, Feng Guo-Dong
Department of Otorhinolaryngology - Head and Neck Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
World J Clin Cases. 2022 May 26;10(15):4991-4997. doi: 10.12998/wjcc.v10.i15.4991.
Paraganglioma occurring at the lateral skull base is a rare tumor. Surgery is the primary treatment of benign paragangliomas. Postoperative infection of the surgical site at the lateral skull base is very dangerous and hard to manage.
A 30-year-old man with a 1-year history of left-side progressive hearing loss, tinnitus, facial palsy, and choking failed conventional treatment and is the focus of this case report. Imaging revealed a mass around the left jugular foramen that was approximately 47 mm × 38 mm × 34 mm in size and had eroded the bone of the vertebral and horizontal segments of the internal carotid artery. The tumor breached the meninges and occupied the cerebella pontine region. A two-stage surgery was designed for the resection of the mass. In the first-stage, the epidural portion of the mass was removed. The abdominal fat and the temporal muscle flap were transposed within the surgical site. The surgery was successful; however, 25 d after surgery, he developed suppurative parotitis, and the infection spread to the surgical site at the skull base. Broad-spectrum antibiotics were used, and debridement was deployed. After that, the wound was cleaned daily. Five months after the first-stage surgery, the wound was still unclosed, and there was intermittent purulent exudation within the surgical site. vacuum sealing drainage (VSD) was used, and the wound healed in a month. One year after the first surgery, the second-stage of the operation was performed to remove the intracranial portion of the tumor. Recurrence of the tumor was not detected after a 6-month follow-up.
After a lateral skull base surgery, suppurative parotitis can spread into the operative cavity leading to infection of the surgical site. VSD can help to effectively heal the infected wound. A two-stage surgical approach offers a safer option for removing the lateral skull base paraganglioma that involves the meninges.
发生于侧颅底的副神经节瘤是一种罕见肿瘤。手术是良性副神经节瘤的主要治疗方法。侧颅底手术部位的术后感染非常危险且难以处理。
一名30岁男性,有1年左侧进行性听力减退、耳鸣、面瘫及呛咳病史,常规治疗无效,是本病例报告的重点。影像学检查显示左侧颈静脉孔周围有一肿块,大小约为47 mm×38 mm×34 mm,已侵蚀颈内动脉椎体段和水平段骨质。肿瘤突破脑膜,占据桥小脑区。设计了两阶段手术切除肿块。第一阶段,切除肿块的硬膜外部分。将腹部脂肪和颞肌瓣转移至手术部位。手术成功;然而,术后25天,他发生了化脓性腮腺炎,感染蔓延至颅底手术部位。使用了广谱抗生素,并进行了清创。此后,每天清洁伤口。第一阶段手术后5个月,伤口仍未愈合,手术部位有间歇性脓性渗出。采用了封闭式负压引流(VSD),伤口在1个月内愈合。第一次手术后1年,进行了第二阶段手术,切除肿瘤的颅内部分。6个月随访后未发现肿瘤复发。
侧颅底手术后,化脓性腮腺炎可蔓延至手术腔隙,导致手术部位感染。VSD有助于有效治愈感染伤口。两阶段手术方法为切除累及脑膜的侧颅底副神经节瘤提供了更安全的选择。