Fejzic Hanifa, Izic Belkisa, Konrad-Custovic Maja
Department of Radiology and Nuclear Medicine, University Clinical Center Tuzla Tuzla, Bosnia and Herzegovina.
Department of Pathology, University Clinical Center Tuzla Tuzla, Bosnia and Herzegovina.
Mater Sociomed. 2022 Mar;34(1):66-69. doi: 10.5455/msm.2022.33.66-69.
Sonography plays an important role in characterizing breast masses and in guiding needle core biopsies and wire localizations of suspicious sonographis abnormalities.
The aim of this study was to show the possibilities of high frequency ultrasound devices in the presentation of microcalcifications of the breast, and the use of these possibilities in performing needle biopsy under ultrasound control.
This was a retrospective study conducted from May 2017 to December 2020 on 32 women, 29-86 years of age using mammograms and ultrasound to show suspected microcalcifications (radiological findings of BI RADS 4B and 4C), and needle biopsy led by ultrasound that confirmed the diagnosis of breast cancer. Patients with suspected microcalcifications on mammography that had previously had the diagnosis of breast cancer confirmed in the same or contralateral breast were excluded from the study. Histology results from each core biopsy and surgical excision were reviewed. The positive predictive values of sonography and mammography for this population were calculated, and the sensitivity, specificity, and negative predictive value of sonography were determined. For analysis of the agreement of ultrasound findings with mammography the McNemar x-test for dependent samples was used.
The sensitivity of mammography in the detection of microcalcifications in this study was 100%. The sensitivity of the ultrasound apparatus with a high frequency probe in the detection of microcalcifications after mammography examination in this study was 87.55%, while the specificity was 42.85%.
Ultrasonic devices with high-frequency probes enable the display of accumulations of microcalcifications previously verified by mammography, and thus enable the performance of needle biopsy of suspected microcalcifications under ultrasonic control. An alternative is the much more complicated and significantly more expensive stereotactic biopsy under the control of mammography.
超声检查在乳腺肿块的特征性描述以及引导针芯活检和对可疑超声异常进行金属丝定位方面发挥着重要作用。
本研究的目的是展示高频超声设备在显示乳腺微钙化方面的可能性，以及在超声引导下进行针吸活检时利用这些可能性。
这是一项回顾性研究，于2017年5月至2020年12月对32名年龄在29至86岁的女性进行，使用乳房X线照片和超声来显示可疑微钙化（乳腺影像报告和数据系统4B和4C级的放射学表现），并通过超声引导的针吸活检确诊为乳腺癌。之前在同侧或对侧乳房已确诊为乳腺癌的乳房X线照片上有可疑微钙化的患者被排除在研究之外。对每次针芯活检和手术切除的组织学结果进行了复查。计算了该人群超声检查和乳房X线照片的阳性预测值，并确定了超声检查的敏感性、特异性和阴性预测值。为分析超声检查结果与乳房X线照片的一致性，使用了配对样本的McNemar x检验。
本研究中乳房X线照片检测微钙化的敏感性为100%。本研究中，在乳房X线照片检查后，使用高频探头的超声设备检测微钙化的敏感性为87.55%，而特异性为42.85%。
带有高频探头的超声设备能够显示先前经乳房X线照片证实的微钙化聚集，从而能够在超声引导下对可疑微钙化进行针吸活检。另一种选择是在乳房X线照片引导下进行更为复杂且明显更昂贵的立体定向活检。
