School of Chemistry and Chemical Engineering, Ningxia University, 489 Helanshan West Road, Yinchuan 750021, People's Republic of China.
State Key Laboratory of High-Efficiency Utilization of Coal and Green Chemical Engineering, School of Chemistry and Chemical Engineering, Ningxia University, Yinchuan, PR China.
Org Biomol Chem. 2022 Jul 27;20(29):5759-5763. doi: 10.1039/d2ob00863g.
The first Ir(I)-catalyzed thioamide-assisted C-H arylation of ferrocenes with aryl boronic acids under base-free mild reaction conditions in the presence of AgCO as an oxidant with eco-friendly 2-MeTHF as a solvent was developed. This reaction has a wide range of substrates (37 examples) and functional group tolerance (18-94% yields), and provides promising access to aryl thioamide-ferrocene compounds with good yields and regioselectivity.
发展了一种在无碱温和反应条件下，以 AgCO3 为氧化剂、环保的 2-MeTHF 为溶剂，在第一例 Ir(I)-催化下、硫代酰胺辅助的二茂铁与芳基硼酸的 C-H 芳基化反应。该反应具有广泛的底物适用性（37 个例子）和官能团容忍性（产率 18-94%），为高产率和区域选择性地获得芳基硫代酰胺-二茂铁化合物提供了有前景的途径。
