Department of Anesthesiology & Pain Medicine, UTHealth McGovern Medical School, Houston, TX 77030, USA.
Pain Manag. 2022 Sep;12(6):681-685. doi: 10.2217/pmt-2021-0120. Epub 2022 Jul 8.
Congenital lipomatous overgrowth, vascular malformations, epidermal nevi and scoliosis/skeletal/spinal anomalies (CLOVES) syndrome is an extremely rare overgrowth syndrome characterized by complex vascular malformations. Management requires an interdisciplinary approach including debulking operations for tissue overgrowth, embolization therapy for vascular malformations and management of chronic pain due to congenital and recurrent vascular overgrowth and from scar tissue from surgical interventions. Here, we present a 35-year-old female with complex medical history due to CLOVES syndrome, with large vascular malformations on her chest, status post debulking/embolization previously and now with continued chronic nociceptive and neuropathic pain, largely due to the recurrent nature of vascular malformations, but now finding some relief with fluoroscopy-guided intercostal nerve blocks which she never experienced before.
先天性脂肪过多性过度生长、血管畸形、表皮痣和脊柱侧凸/骨骼/脊髓异常（CLOVES）综合征是一种极其罕见的过度生长综合征，其特征为复杂的血管畸形。管理需要采用多学科方法，包括对组织过度生长进行切除术、对血管畸形进行栓塞治疗，以及管理由于先天性和复发性血管过度生长以及手术干预后的疤痕组织引起的慢性疼痛。在这里，我们介绍了一位 35 岁的女性，患有 CLOVES 综合征，胸部有复杂的血管畸形，之前进行过切除术/栓塞术，现在仍有持续的慢性伤害性和神经性疼痛，主要是由于血管畸形的复发性，但现在通过透视引导肋间神经阻滞术获得了一些缓解，她以前从未经历过这种治疗。
