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激光周边虹膜切开术后使用毛果芸香碱在难治性急性闭角型青光眼眼中的作用:病例报告及文献复习。

Role of pilocarpine use following laser peripheral iridotomy in eyes with refractory acute angle closure glaucoma: A case report and literature review.

机构信息

Department of Ophthalmology, Taipei City Hospital, Renai Branch, Taipei, Taiwan.

Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.

出版信息

Medicine (Baltimore). 2022 Jul 8;101(27):e29245. doi: 10.1097/MD.0000000000029245.

Abstract

RATIONALE

Angle closure glaucoma (ACG) is one of the most emergent types of glaucoma in clinical practice. Laser peripheral iridotomy (LPI) could minimize pupillary block and prevent ACG from an acute attack. However, recurrent increase in intraocular pressure (IOP) may still occur despite successful LPI. The aim of this study is to highlight the importance of postLPI pilocarpine use and larger LPI size as well as to share some experiences of cataract surgery in patients with ACG.

PATIENT CONCERNS

A 63-year-old female was referred to our hospital for headache, and poor control of IOP in the right eye for 3 hours.

DIAGNOSES

The patient was diagnosed ACG in the right eye. Recurrence of ACG in the right eye and new-onset and recurrent ACG in the left eye were noted during follow-up, despite successful LPI. The diagnosis was confirmed through slit lamp and gonioscope examination.

INTERVENTIONS

The LPI size was enlarged and pilocarpine use was maintained at 2% (1 drop 4 times a day) in both the eyes. Finally, cataract surgery was performed in both the eyes.

OUTCOMES

No recurrence of ACG was noted during postLPI pilocarpine use in both the eyes. The postoperative IOP was stable for >6 months after cataract surgery without any surgical intervention or antiglaucoma medication use. No discomfort or major complication was observed.

CONCLUSION

This report highlights the importance of postLPI pilocarpine use and larger LPI size in patients with refractory ACG.

摘要

背景

闭角型青光眼(ACG)是临床实践中最紧急的青光眼类型之一。激光周边虹膜切开术(LPI)可以最小化瞳孔阻滞,并防止 ACG 急性发作。然而,尽管 LPI 成功,眼内压(IOP)仍可能反复升高。本研究旨在强调 LPI 后毛果芸香碱使用和更大的 LPI 大小的重要性,并分享一些 ACG 患者白内障手术的经验。

患者关注

一位 63 岁女性因头痛和右眼 IOP 控制不佳 3 小时就诊于我院。

诊断

右眼诊断为 ACG。尽管 LPI 成功,但在随访中发现右眼 ACG 复发,左眼新发和复发性 ACG。通过裂隙灯和房角镜检查确诊。

干预

双眼 LPI 大小增大,并维持毛果芸香碱使用 2%(每日 4 滴)。最终,双眼均行白内障手术。

结果

双眼 LPI 后使用毛果芸香碱无 ACG 复发。白内障手术后,IOP 在 6 个月以上稳定,无需手术干预或抗青光眼药物治疗。未观察到不适或主要并发症。

结论

本报告强调了在难治性 ACG 患者中,LPI 后毛果芸香碱使用和更大的 LPI 大小的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2160/9259105/67363e724202/medi-101-e29245-g001.jpg

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