• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

激光周边虹膜切开术后使用毛果芸香碱在难治性急性闭角型青光眼眼中的作用:病例报告及文献复习。

Role of pilocarpine use following laser peripheral iridotomy in eyes with refractory acute angle closure glaucoma: A case report and literature review.

机构信息

Department of Ophthalmology, Taipei City Hospital, Renai Branch, Taipei, Taiwan.

Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.

出版信息

Medicine (Baltimore). 2022 Jul 8;101(27):e29245. doi: 10.1097/MD.0000000000029245.

DOI:10.1097/MD.0000000000029245
PMID:35801778
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9259105/
Abstract

RATIONALE

Angle closure glaucoma (ACG) is one of the most emergent types of glaucoma in clinical practice. Laser peripheral iridotomy (LPI) could minimize pupillary block and prevent ACG from an acute attack. However, recurrent increase in intraocular pressure (IOP) may still occur despite successful LPI. The aim of this study is to highlight the importance of postLPI pilocarpine use and larger LPI size as well as to share some experiences of cataract surgery in patients with ACG.

PATIENT CONCERNS

A 63-year-old female was referred to our hospital for headache, and poor control of IOP in the right eye for 3 hours.

DIAGNOSES

The patient was diagnosed ACG in the right eye. Recurrence of ACG in the right eye and new-onset and recurrent ACG in the left eye were noted during follow-up, despite successful LPI. The diagnosis was confirmed through slit lamp and gonioscope examination.

INTERVENTIONS

The LPI size was enlarged and pilocarpine use was maintained at 2% (1 drop 4 times a day) in both the eyes. Finally, cataract surgery was performed in both the eyes.

OUTCOMES

No recurrence of ACG was noted during postLPI pilocarpine use in both the eyes. The postoperative IOP was stable for >6 months after cataract surgery without any surgical intervention or antiglaucoma medication use. No discomfort or major complication was observed.

CONCLUSION

This report highlights the importance of postLPI pilocarpine use and larger LPI size in patients with refractory ACG.

摘要

背景

闭角型青光眼(ACG)是临床实践中最紧急的青光眼类型之一。激光周边虹膜切开术(LPI)可以最小化瞳孔阻滞,并防止 ACG 急性发作。然而,尽管 LPI 成功,眼内压(IOP)仍可能反复升高。本研究旨在强调 LPI 后毛果芸香碱使用和更大的 LPI 大小的重要性,并分享一些 ACG 患者白内障手术的经验。

患者关注

一位 63 岁女性因头痛和右眼 IOP 控制不佳 3 小时就诊于我院。

诊断

右眼诊断为 ACG。尽管 LPI 成功,但在随访中发现右眼 ACG 复发,左眼新发和复发性 ACG。通过裂隙灯和房角镜检查确诊。

干预

双眼 LPI 大小增大,并维持毛果芸香碱使用 2%(每日 4 滴)。最终,双眼均行白内障手术。

结果

双眼 LPI 后使用毛果芸香碱无 ACG 复发。白内障手术后,IOP 在 6 个月以上稳定,无需手术干预或抗青光眼药物治疗。未观察到不适或主要并发症。

结论

本报告强调了在难治性 ACG 患者中,LPI 后毛果芸香碱使用和更大的 LPI 大小的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2160/9259105/a4eae53a0282/medi-101-e29245-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2160/9259105/67363e724202/medi-101-e29245-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2160/9259105/180cf1883c35/medi-101-e29245-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2160/9259105/e8a65e2b4911/medi-101-e29245-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2160/9259105/a4eae53a0282/medi-101-e29245-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2160/9259105/67363e724202/medi-101-e29245-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2160/9259105/180cf1883c35/medi-101-e29245-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2160/9259105/e8a65e2b4911/medi-101-e29245-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2160/9259105/a4eae53a0282/medi-101-e29245-g004.jpg

相似文献

1
Role of pilocarpine use following laser peripheral iridotomy in eyes with refractory acute angle closure glaucoma: A case report and literature review.激光周边虹膜切开术后使用毛果芸香碱在难治性急性闭角型青光眼眼中的作用:病例报告及文献复习。
Medicine (Baltimore). 2022 Jul 8;101(27):e29245. doi: 10.1097/MD.0000000000029245.
2
Acute primary angle closure in an Asian population: long-term outcome of the fellow eye after prophylactic laser peripheral iridotomy.亚洲人群中的急性原发性闭角型青光眼:预防性激光周边虹膜切开术后对侧眼的长期预后
Ophthalmology. 2000 Nov;107(11):2092-6. doi: 10.1016/s0161-6420(00)00360-2.
3
Optical coherence tomography-measured changes over time in anterior chamber angle and diurnal intraocular pressure after laser iridotomy: IMPACT study.激光虹膜切开术后前房角和日间眼压的光学相干断层扫描测量时间变化:IMPACT 研究。
Clin Exp Ophthalmol. 2018 Nov;46(8):895-902. doi: 10.1111/ceo.13303. Epub 2018 May 16.
4
Laser Peripheral Iridotomy in Primary Angle Closure: A Report by the American Academy of Ophthalmology.激光周边虹膜切开术治疗原发性闭角型青光眼:美国眼科学会报告。
Ophthalmology. 2018 Jul;125(7):1110-1120. doi: 10.1016/j.ophtha.2018.01.015. Epub 2018 Mar 2.
5
Laser peripheral iridotomy versus laser peripheral iridotomy plus laser peripheral iridoplasty in the treatment of multi-mechanism angle closure: study protocol for a randomized controlled trial.激光周边虹膜切开术与激光周边虹膜切开术联合激光周边虹膜成形术治疗多机制性房角关闭:一项随机对照试验的研究方案
Trials. 2017 Mar 17;18(1):130. doi: 10.1186/s13063-017-1860-4.
6
Follow-up of angle closure glaucoma suspects after laser iridotomy in Caucasians with normal intraocular pressure at diagnosis.对诊断时眼压正常的白种人闭角型青光眼疑似患者行激光虹膜切开术后的随访。
Can J Ophthalmol. 2011 Jun;46(3):247-53. doi: 10.1016/j.jcjo.2011.05.014. Epub 2011 May 27.
7
Recurrent acute angle-closure attack due to plateau iris syndrome after cataract extraction with or without argon laser peripheral iridoplasty: a case report.白内障摘除术后伴或不伴氩激光周边虹膜成形术所致高原虹膜综合征引起的复发性急性闭角型发作:一例报告
BMC Ophthalmol. 2016 May 26;16:64. doi: 10.1186/s12886-016-0244-y.
8
The rarity of clinically significant rise in intraocular pressure after laser peripheral iridotomy with apraclonidine.使用阿可乐定进行激光周边虹膜切开术后眼压出现具有临床意义升高的情况罕见。
Ophthalmology. 1998 Dec;105(12):2256-9. doi: 10.1016/S0161-6420(98)91225-8.
9
Factors Associated with Interventions after Laser Peripheral Iridotomy for Primary Angle-Closure Spectrum Diagnoses.与原发性闭角型青光眼谱系诊断的激光周边虹膜切开术后干预相关的因素。
Ophthalmol Glaucoma. 2019 May-Jun;2(3):192-200. doi: 10.1016/j.ogla.2019.03.003. Epub 2019 Mar 16.
10
Anterior chamber morphology changes in eyes with narrow angles by Scheimpflug imaging: Pilocarpine versus laser peripheral iridotomy.Scheimpflug 成像观察缩瞳剂与激光周边虹膜切开术对窄房角眼眼前房形态的影响。
Int Ophthalmol. 2021 Jun;41(6):2099-2108. doi: 10.1007/s10792-021-01767-4. Epub 2021 Mar 24.

引用本文的文献

1
Effects of selected alkaloids on postnatal neurogenesis - in vivo and in vitro studies - literature review.所选生物碱对产后神经发生的影响——体内和体外研究——文献综述
Psychopharmacology (Berl). 2025 Jul 28. doi: 10.1007/s00213-025-06856-1.
2
Unraveling Nature's Pharmacy: Transforming Medicinal Plants into Modern Therapeutic Agents.揭开自然药房的奥秘:将药用植物转化为现代治疗药物。
Pharmaceutics. 2025 Jun 7;17(6):754. doi: 10.3390/pharmaceutics17060754.
3
Ocular Distribution of Brimonidine and Brinzolamide after Topical Instillation of a 0.1% Brimonidine Tartrate and 1% Brinzolamide Fixed-Combination Ophthalmic Suspension: An Interventional Study.
0.1%酒石酸溴莫尼定和1%布林佐胺固定复方眼用混悬液局部滴注后溴莫尼定和布林佐胺的眼内分布:一项干预性研究。
J Clin Med. 2023 Jun 21;12(13):4175. doi: 10.3390/jcm12134175.