全球范围内对痉挛性疾病患者接受肉毒毒素注射后辅助治疗使用情况的临床医师实践调查

Worldwide Survey of Clinician Practice on use of Adjunctive Therapies Following Botulinum Toxin Injection for Spasticity.

机构信息

Rehabilitation Centre Pellenberg, University Hospitals Leuven, Leuven, Belgium.

Division of Physical Medicine and Rehabilitation, Department of Medicine, University of British Columbia, GF Strong Rehabilitation Centre, International Collaboration on Repair Discoveries (ICORD), Vancouver, BC, Canada.

出版信息

J Rehabil Med. 2022 Sep 19;54:jrm00320. doi: 10.2340/jrm.v54.334.

Abstract

OBJECTIVE

Non-pharmacological adjunctive therapies can be used alongside botulinum toxin injection to enhance its efficacy. The objective of this global study was to determine the current practice and perception among clinicians of the use of adjunctive therapies after botulinum toxin injections for the treatment of limb spasticity.

METHODS

A questionnaire with 22 questions on clinical practice demographics, self-reported use and clinician opinion on barriers to the use of complementary therapies, and priorities for future research was translated into 7 languages and distributed worldwide through national and international professional associations concerning (neuro)rehabilitation.

RESULTS

A total of 527 clinicians from 52 countries responded to the survey. Most commonly used physical interventions were: active exercise programmes at home (81%), stretching programmes at home (81%), and splinting (70%), followed by active movement exercises (65%) and within 30 min of botulinum toxin injection and constraint induced movement therapy (63%). The main barriers reported by clinicians to provision of these interventions were clinicians' lack of time, limited financial resources, and lack of evidence. Future research should focus primarily on immediate active movement exercises and passive stretching.

CONCLUSION

Worldwide, clinicians often recommend adjunctive therapies after a botulinum toxin injection to reduce spasticity. The most commonly used physical interventions among clinicians were active exercises at home, stretching at home, and splinting. Lack of evidence, time and financial constraints were identified as barriers to providing these interventions.

摘要

目的

非药物辅助疗法可与肉毒毒素注射联合使用,以增强其疗效。本全球研究旨在确定临床医生在使用肉毒毒素治疗肢体痉挛后,对辅助治疗的应用现状和看法。

方法

通过国家和国际(神经)康复专业协会,将一份包含 22 个问题的问卷翻译成 7 种语言,在全球范围内进行发放,内容涉及临床实践人口统计学、自我报告的使用情况以及对补充治疗使用障碍的看法,以及未来研究的重点。

结果

共有来自 52 个国家的 527 名临床医生对该调查做出了回应。最常使用的物理干预措施包括:在家中进行主动运动计划(81%)、在家中进行伸展计划(81%)和夹板固定(70%),其次是主动运动(65%)和肉毒毒素注射后 30 分钟内以及约束诱导运动疗法(63%)。临床医生提供这些干预措施的主要障碍是临床医生缺乏时间、有限的财务资源和缺乏证据。未来的研究应主要集中在即时主动运动和被动伸展上。

结论

在全球范围内,临床医生经常在肉毒毒素注射后建议使用辅助疗法来减轻痉挛。临床医生最常使用的物理干预措施是在家中进行主动运动、在家中进行伸展运动和夹板固定。缺乏证据、时间和财务限制被认为是提供这些干预措施的障碍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e54/9511365/595cbcb6439e/JRM-54-334-g001.jpg

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