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糖皮质激素对兔颈动脉体的影响。

Effects of glucocorticoids on the rabbit carotid body.

作者信息

Smith P, Greenberg S, Heath D, Gosney J

出版信息

Br J Exp Pathol. 1987 Apr;68(2):251-8.

Abstract

Weekly intramuscular injections of slow-release, depot methyl prednisolone to 15 adult Dutch rabbits did not bring about an increase in the volume of their carotid bodies. However, they caused swelling of chief cells with discrete areas of pallor in the cytoplasm. Factors responsible for these changes appear to be increased storage of catecholamines and an increased number of swollen mitochondria.

摘要

对15只成年荷兰兔每周进行一次缓释长效甲基强的松龙肌肉注射,并未使其颈动脉体体积增大。然而,这导致主细胞肿胀,细胞质中出现离散的苍白区域。造成这些变化的因素似乎是儿茶酚胺储存增加和肿胀线粒体数量增多。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a35/2013018/751ad1f8118a/brjexppathol00008-0116-a.jpg

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