糖皮质激素对兔颈动脉体的影响。
Effects of glucocorticoids on the rabbit carotid body.
作者信息
Smith P, Greenberg S, Heath D, Gosney J
出版信息
Br J Exp Pathol. 1987 Apr;68(2):251-8.
Abstract
Weekly intramuscular injections of slow-release, depot methyl prednisolone to 15 adult Dutch rabbits did not bring about an increase in the volume of their carotid bodies. However, they caused swelling of chief cells with discrete areas of pallor in the cytoplasm. Factors responsible for these changes appear to be increased storage of catecholamines and an increased number of swollen mitochondria.
摘要
对15只成年荷兰兔每周进行一次缓释长效甲基强的松龙肌肉注射，并未使其颈动脉体体积增大。然而，这导致主细胞肿胀，细胞质中出现离散的苍白区域。造成这些变化的因素似乎是儿茶酚胺储存增加和肿胀线粒体数量增多。
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本文引用的文献
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Localization of enkephalin-like immunoreactivity in the cat carotid and aortic body chemoreceptors.脑啡肽样免疫反应在猫颈动脉体和主动脉体化学感受器中的定位。
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Effects of hypoxia and glucocorticoids on the histochemically demonstrable catecholamines of the newborn rat carotid body.缺氧和糖皮质激素对新生大鼠颈动脉体组织化学可显示的儿茶酚胺的影响。
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Effect of corticosteroid on hyperactive carotid body and carotid sinus in asthmatics.
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Fine structure of rat carotid body after 6-methylprednisolone treatment.6-甲基泼尼松龙治疗后大鼠颈动脉体的精细结构
Int J Neurosci. 1973;6(3):109-15. doi: 10.3109/00207457309147654.
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The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept.APUD系列中产生多肽激素细胞的细胞化学与超微结构以及该概念的胚胎学、生理学和病理学意义。
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Histochemically demonstrable increase in the catecholamine content of the carotid body in adult rats treated with methylprednisolone or hydrocortisone.用甲基泼尼松龙或氢化可的松处理的成年大鼠，其颈动脉体中儿茶酚胺含量在组织化学上可证实增加。
Histochem J. 1973 Sep;5(5):479-85. doi: 10.1007/BF01012005.
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Brain Res. 1976 Feb 6;102(2):245-54. doi: 10.1016/0006-8993(76)90880-5.
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