Department of Neuropsychiatry, National Institute of Neurology and Neurosurgery, Mexico.
Department of Neuropsychiatry, National Institute of Neurology and Neurosurgery, Mexico.
Rev Colomb Psiquiatr (Engl Ed). 2022 Apr-Jun;51(2):163-166. doi: 10.1016/j.rcpeng.2020.10.006.
Inhalant users may develop toluene leukoencephalopathy, a devastating neuropsychiatric disorder. We present a case of toluene-induced damage to the corticospinal and the corticonuclear tracts, which presented with involuntary emotional expression disorder.
Case study of a 20-year-old man with a 3-year history of frequent solvent abuse was admitted to the Neuropsychiatry Unit of the National Institute of Neurology and Neurosurgery because "he could not speak or walk" but would keep "laughing and crying without reason".
Neuropsychiatric examination revealed pathological laughter and crying, facial and speech apraxia, a bilateral pyramidal syndrome, and lack of control of urinary sphincter. Magnetic resonance imaging revealed a highly selective bilateral damage to the pyramidal system and the somatosensory pathway. SPECT imaging showed left fronto-parietal hypoperfusion.
This document provides support for the understanding of involuntary emotional expression disorders as a differential diagnosis in the clinical practice of psychiatrists, as well as the functional anatomy of these conditions.
吸入剂使用者可能会患上甲苯性脑白质病，这是一种严重的神经精神疾病。我们报告了一例因甲苯引起的皮质脊髓束和皮质核束损伤的病例，该患者表现为不自主的情感表达障碍。
对一名 20 岁、有 3 年频繁滥用溶剂史的男性进行了病例研究，该患者因“无法说话或行走”但会“无缘无故地大笑和哭泣”而被收入神经病学和神经外科学院的神经精神病学病房。
神经精神检查显示病理性大笑和哭泣、面和言语失用症、双侧锥体束征和尿失禁控制缺失。磁共振成像显示双侧锥体系统和感觉通路高度选择性损伤。SPECT 成像显示左额顶叶灌注不足。
本文为理解不自主情感表达障碍作为精神科医生临床实践中的鉴别诊断以及这些疾病的功能解剖学提供了支持。
