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人谷胱甘肽S-转移酶。红细胞酶的动力学、稳定性及抑制特性研究。

The human glutathione S-transferase. Studies on the kinetic, stability and inhibition characteristics of the erythrocyte enzyme.

作者信息

Hirrell P A, Collins M F, Nimmo I A, Strange R C

出版信息

Biochim Biophys Acta. 1987 May 27;913(1):92-6. doi: 10.1016/0167-4838(87)90237-8.

DOI:10.1016/0167-4838(87)90237-8
PMID:3580378
Abstract

Bromosulphophthalein and N-ethylmaleimide, inhibitors of glutathione S-transferase (EC 2.5.1.18 RX: glutathione R. transferase), have been used to identify variant forms of the erythrocyte enzyme. One 'atypical' sample was detected and was shown to have appreciably different kinetic and stability properties. These inhibitors may be useful in surveys of variation in this group of enzymes.

摘要

溴磺酞和N-乙基马来酰亚胺,谷胱甘肽S-转移酶(EC 2.5.1.18 RX:谷胱甘肽R.转移酶)的抑制剂,已被用于鉴定红细胞酶的变异形式。检测到一个“非典型”样本,其动力学和稳定性特性明显不同。这些抑制剂可能有助于对这组酶的变异进行调查。

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Biochim Biophys Acta. 1987 May 27;913(1):92-6. doi: 10.1016/0167-4838(87)90237-8.
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