• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

[Inhibition of microsomal oxidation by o-benzoquinone derivatives].

作者信息

Kostiuk V A

出版信息

Biokhimiia. 1987 Mar;52(3):355-8.

PMID:3580408
Abstract

It was found that o-benzoquinone derivatives inhibit the hydroxylation of aniline without any appreciable influence on the spectral changes which are due to cytochrome P-450 binding to the substrate. A comparative kinetic study of inhibition of aniline hydroxylation and NADPH-dependent reduction of o-benzoquinones in liver microsomes revealed that the inhibition is due to the ability of these compounds to shunt microsomal electron transport pathways.

摘要

相似文献

1
[Inhibition of microsomal oxidation by o-benzoquinone derivatives].
Biokhimiia. 1987 Mar;52(3):355-8.
2
[Inhibition of lipid peroxidation by derivatives of o-benzoquinone in liver microsomes].
Biokhimiia. 1983 Sep;48(9):1491-5.
3
[Antioxidative effect of o-benzoquinone derivatives during CCl4-induced lipid peroxidation in the rat liver].[邻苯醌衍生物在四氯化碳诱导的大鼠肝脂质过氧化过程中的抗氧化作用]
Biokhimiia. 1988 Feb;53(2):233-7.
4
[Interaction in vitro of nicotinamide and diethylnicotinamid (cordiamine) with enzymes of the liver microsomal hydoxylating system in the rat].[烟酰胺和二乙烟酰胺（可拉明）与大鼠肝脏微粒体羟化系统酶的体外相互作用]
Farmakol Toksikol. 1985 Mar-Apr;48(2):97-100.
5
[Effect of monooxygenase reactions catalyzed by cytochrome P-450 on the microsomal membrane].[细胞色素P-450催化的单加氧酶反应对微粒体膜的影响]
Biokhimiia. 1987 Jul;52(7):1090-6.
6
Perinatal development of tertiary amine N-oxidation and NADPH cytochrome C reduction in rat liver microsomes.大鼠肝微粒体中叔胺N-氧化和NADPH细胞色素C还原的围产期发育。
Res Commun Chem Pathol Pharmacol. 1971 Nov;2(6):793-805.
7
Involvement of singlet oxygen in cytochrome P450-dependent substrate oxidations.单线态氧参与细胞色素P450依赖性底物氧化反应。
Biochem Biophys Res Commun. 1999 Sep 24;263(2):392-7. doi: 10.1006/bbrc.1999.1384.
8
Involvement of a hydrophobic site in the inhibition of the microsomal p-hydroxylation of aniline by alcohols.疏水位点参与醇类对微粒体苯胺对羟基化作用的抑制过程。
Mol Pharmacol. 1973 May;9(3):383-97.
9
[Effect of phospholipids on the activity of highly-purified liver microsome cytochrome P-450 in a reaction of aniline and naphthalene hydroxylation by hydroperoxides].[磷脂对氢过氧化物在苯胺和萘羟基化反应中高纯度肝微粒体细胞色素P - 450活性的影响]
Prikl Biokhim Mikrobiol. 1980 Jan-Feb;16(1):100-5.
10
[Comparative inhibitory analysis of aniline hydroxylation by cytochrome P-450 in NADPH-, hydroperoxide cumyl- and H2O2-dependent systems].
Biokhimiia. 1983 Nov;48(11):1788-93.