Acute second trimester EPH (edema/proteinuria/hypertension) gestosis as an indicator of fetal anomaly.

EPH gestosis in the second trimester suggests the likelihood of a number of fetal anomalies; the status of the fetus and risk to mother are such that spontaneous delivery or hysterotomy is usually the outcome, often without a full prenatal investigation. The types of fetal disorders encountered in this clinical setting are listed. Effects of abnormal endocrine environment as well as primary fetal malformations are distinguishable in these fetuses.