Caqueo-Urízar Alejandra, Ponce-Correa Felipe, Semir-González Carla, Urzúa Alfonso
Instituto de Alta Investigación, Universidad de Tarapacá, Arica 1000000, Chile.
Programa Doctorado en Psicología, Escuela de Psicología y Filosofía, Universidad de Tarapacá, Arica 1000000, Chile.
J Clin Med. 2022 Jul 2;11(13):3840. doi: 10.3390/jcm11133840.
Premorbid adjustment (PA) has classically been defined as psychosocial functioning in the areas of education, occupation, social and interpersonal relationships prior to evidence of characteristic positive symptomatology. It is a concept which possesses ample evidence regarding its predictive nature for the course of Schizophrenia. The study aimed to analyze the latent profiles of premorbid adjustment and their relationship with symptomatology, functionality, subjective recovery, stigma resistance and years of untreated psychosis. Latent class analysis (LCA) was used to elaborate a solution of three premorbid adjustment profiles in a sample of 217 patients diagnosed with Schizophrenia from Public Mental Health Centers in the city of Arica, Chile. The results show that premorbid adjustment was significantly correlated with recovery indicators and that latent profiles of better premorbid adjustment predict better outcomes in subjective recovery and stigma resistance. The results show that premorbid adjustment not only has implications for the severity of the disorder, but that psychosocial functioning prior to psychosis affects the patient's subjectivity, the representation of the disorder and the recovery process.
病前调适（PA）传统上被定义为在出现典型阳性症状之前，个体在教育、职业、社会及人际关系等领域的心理社会功能。这一概念对于精神分裂症病程的预测性质有着充分的证据支持。该研究旨在分析病前调适的潜在类别及其与症状、功能、主观康复、抗耻辱感及未治疗精神病年限之间的关系。在来自智利阿里卡市公共心理健康中心的217例被诊断为精神分裂症的患者样本中，采用潜在类别分析（LCA）得出了三种病前调适类别的结果。结果表明，病前调适与康复指标显著相关，且病前调适较好的潜在类别预示着在主观康复和抗耻辱感方面有更好的结果。结果显示，病前调适不仅对疾病的严重程度有影响，而且精神病发作前的心理社会功能会影响患者的主观性、对疾病的认知及康复过程。
