Jones D A, Notley H M, Hunter R D
Br J Radiol. 1987 May;60(713):481-5. doi: 10.1259/0007-1285-60-713-481.
Twenty-eight patients with early-stage carcinoma of the uterine cervix were treated using one standard Manchester radium application and one afterloading Selectron application. In each case, radiographs were analysed to determine differences in geometry of applicators relative to each other, or to the bony pelvis. During the Selectron treatment the applicators lay significantly more anterior in the pelvis, with a reduced angulation between the axes of the uterus and the vagina. The separation between the ovoids was increased. An identical analysis of 25 patients who had received two radium applications showed that the uterine tube lay significantly more anterior in the pelvis during the second application. Reasons for these differences and their possible clinical importance in terms of increased dose rate to critical tissue are discussed.
28例早期子宫颈癌患者接受了一次标准的曼彻斯特镭敷贴治疗和一次后装施源器治疗。在每例患者中，对X线片进行分析，以确定施源器相对于彼此或骨盆骨骼的几何形状差异。在施源器治疗期间，施源器在骨盆中的位置明显更靠前，子宫轴与阴道轴之间的角度减小。卵形体之间的间距增加。对25例接受两次镭敷贴治疗的患者进行的相同分析表明，在第二次敷贴治疗期间，输卵管在骨盆中的位置明显更靠前。讨论了这些差异的原因及其在增加对关键组织的剂量率方面可能的临床重要性。
