Peng Yong, Deng Xiang, Yang Shan-Shan, Nie Wei, Tang Yan-Dan
Department of Neurology, Affiliated First Hospital of Hunan Traditional Chinese Medical College, Zhuzhou, Hunan Province, 412000, China.
Chin J Integr Med. 2023 Jan;29(1):89-95. doi: 10.1007/s11655-022-3535-6. Epub 2022 Jul 9.
The primary chemical components of Astragalus membranaceus include polysaccharides, saponins, flavonoids, and amino acids. Recent studies have shown that Astragalus membranaceus has multiple functions, including improving immune function and exerting antioxidative, anti-radiation, anti-tumor, antibacterial, antiviral, and hormone-like effects. Astragalus membranaceus and its extracts are widely used in clinical practice because they have obvious therapeutic effects against various autoimmune diseases and relatively less adverse reaction. Multiple sclerosis (MS) is an autoimmune disease of central nervous system (CNS), which mainly caused by immune disorder that leads to inflammatory demyelination, inflammatory cell infiltration, and axonal degeneration in the CNS. In this review, the authors analyzed the clinical manifestations of MS and experimental autoimmune encephalomyelitis (EAE) and focused on the efficacy of Astragalus membranaceus and its chemical components in the treatment of MS/EAE.
黄芪的主要化学成分包括多糖、皂苷、黄酮类化合物和氨基酸。最近的研究表明，黄芪具有多种功能，包括提高免疫功能以及发挥抗氧化、抗辐射、抗肿瘤、抗菌、抗病毒和类激素作用。黄芪及其提取物在临床实践中被广泛应用，因为它们对各种自身免疫性疾病具有明显的治疗效果，且不良反应相对较少。多发性硬化症（MS）是一种中枢神经系统（CNS）的自身免疫性疾病，主要由免疫紊乱导致中枢神经系统出现炎性脱髓鞘、炎性细胞浸润和轴突变性引起。在这篇综述中，作者分析了MS和实验性自身免疫性脑脊髓炎（EAE）的临床表现，并重点关注了黄芪及其化学成分在治疗MS/EAE方面的疗效。
Zotero 插件