Departamento de Cirugía General, Hospital Metropolitano "Dr. Bernardo Sepúlveda", Monterrey, Nuevo León, Mexico.
Departamento de Cirugía General, Hospital Metropolitano "Dr. Bernardo Sepúlveda", Monterrey, Nuevo León, Mexico.
Rev Gastroenterol Mex (Engl Ed). 2023 Oct-Dec;88(4):322-332. doi: 10.1016/j.rgmxen.2022.06.005. Epub 2022 Jul 6.
Currently there is no ideal diagnostic/therapeutic approach for patients with suspected choledocholithiasis. The primary aim of our study was to evaluate the performance of the criteria for predicting choledocholithiasis proposed by the American Society for Gastrointestinal Endoscopy (ASGE) in 2019.
A retrospective study was conducted that included 352 patients seen at a secondary care public healthcare institution in Monterrey, Nuevo León, that treats an open population and does not have endoscopic ultrasound or magnetic resonance cholangiopancreatography at its disposal.
The most frequent predictor presented by the patients was abnormal liver function tests (90.63%), and with their use alone, sensitivity was higher than that of all the predictors analyzed (91.41%). In addition, the finding of common bile duct stones on ultrasound imaging was the only predictor independently associated with the confirmatory diagnosis of choledocholithiasis. Regarding the general performance of the 2019 criteria, the high-risk category had 68.75% sensitivity, 52.08% specificity, a positive predictive value of 79.28%, a negative predictive value of 38.46%, diagnostic accuracy of 64.20%, and a confirmatory diagnosis of choledocholithiasis in 79.28% of the patients of that risk category.
The study corroborated that the presence of choledocholithiasis could be predicted using the choledocholithiasis predictors and risk categories proposed by the ASGE, with acceptable accuracy, in accordance with the standards suggested by those same guidelines.
目前,对于疑似胆总管结石的患者,尚无理想的诊断/治疗方法。我们的主要研究目的是评估美国胃肠内镜学会(ASGE)2019 年提出的预测胆总管结石的标准的性能。
进行了一项回顾性研究,纳入了在新莱昂州蒙特雷市一家二级保健公立医疗机构就诊的 352 名患者,该机构治疗的是开放人群,并且没有内镜超声或磁共振胰胆管成像。
患者最常见的预测指标是肝功能异常(90.63%),单独使用该指标,其敏感性高于所有分析的预测指标(91.41%)。此外,超声成像上发现胆总管结石是唯一与胆总管结石确诊相关的预测指标。关于 2019 年标准的总体表现,高危类别有 68.75%的敏感性、52.08%的特异性、79.28%的阳性预测值、38.46%的阴性预测值、64.20%的诊断准确率,以及 79.28%的该风险类别的患者被确诊为胆总管结石。
研究证实,使用 ASGE 提出的胆总管结石预测指标和风险类别可以预测胆总管结石的存在,其准确性符合这些指南建议的标准。