Hirose Yuki, Ueyama Tomoto, Kikuta Shuu, Suzuki Tomofusa, Tateishi Tsubasa, Saito Yuuichi, Sano Hirohito, Abe Keiko, Miura Hideaki, Saito Satoshi
Department of Gastroenterology, Japan Community Health Care Organization, Tokyo Yamate Medical Center.
Department of Pathology, Japan Community Health Care Organization, Tokyo Yamate Medical Center.
Nihon Shokakibyo Gakkai Zasshi. 2022;119(7):666-673. doi: 10.11405/nisshoshi.119.666.
A 74-year-old male with pancreatic cancer and multiple huge liver metastases received palliative care due to the cancer progression after chemotherapy. The patient was admitted to our hospital for increased abdominal pain and dehydration. Tumor lysis syndrome was diagnosed on the fifth hospital day owing to the advancement of renal impairment, hyperuricemia, hyperkalemia, and hyperphosphatemia. The patient's condition rapidly deteriorated despite increased intravenous infusion and the provision of antihyperuricemia medicine and demised on the seventh hospital day. Autopsy results revealed generalized necrosis of the tumor, consistent with tumor lysis syndrome.
