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积极思考:连通性和情感词汇的计算评估如何为精神病早期阶段提供信息。

Happy thoughts: What computational assessment of connectedness and emotional words can inform about early stages of psychosis.

机构信息

Department of Psychiatry and Legal Medicine, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil; Research department at Motrix Lab, Motrix, Rio de Janeiro, Brazil.

Research department at Motrix Lab, Motrix, Rio de Janeiro, Brazil.

出版信息

Schizophr Res. 2023 Sep;259:38-47. doi: 10.1016/j.schres.2022.06.025. Epub 2022 Jul 7.

Abstract

In recent years, different natural language processing tools measured aspects related to narratives' structural, semantic, and emotional content. However, there is a need to better understand the limitations and effectiveness of speech elicitation protocols. The graph-theoretical analysis applied to short narratives reveals lower connectedness associated with negative symptoms even in the early stages of psychosis, but emotional topics seem more informative than others. We investigate the interaction between connectedness and emotional words with negative symptoms and educational level in participants with and without psychosis. For that purpose, we used a speech elicitation protocol based on three positive affective pictures and calculated the proportion of emotional words and connectedness measures in the first-episode psychosis (FEP) group (N: 24) and a control group (N: 33). First, we replicated the association between connectedness and negative symptoms (R: 0.53, p: 0.0049). Second, the more positive terms, the more connected the narrative was, exclusively under psychosis and in association with education, pointing to an interaction between symptoms and formal education. Negative symptoms were independently associated with connectedness, but not with emotional words, although the associations with education were mutually dependent. Together, education and symptoms explained almost 70 % of connectedness variance (R: 0.67, p < 0.0001), but not emotional expression. At this initial stage of psychosis, education seems to play an important role, diminishing the impact of negative symptoms on the narrative connectedness. Negative symptoms in FEP impact narrative connectedness in association with emotional expression, revealing aspects of social cognition through a short and innocuous protocol.

摘要

近年来,不同的自然语言处理工具测量了与叙事的结构、语义和情感内容相关的方面。然而,需要更好地了解言语诱发协议的局限性和有效性。应用于短篇叙事的图论分析揭示了即使在精神病早期也与阴性症状相关的连接性降低,但情绪主题似乎比其他主题更具信息量。我们调查了连接性和情绪词与阴性症状和教育水平在精神病患者和非精神病患者之间的相互作用。为此,我们使用了基于三张正面情感图片的言语诱发协议,并计算了首发精神病(FEP)组(N=24)和对照组(N=33)中情绪词和连接性测量的比例。首先,我们复制了连接性与阴性症状之间的关联(R:0.53,p:0.0049)。其次,积极术语越多,叙事就越连贯,仅在精神病患者中与教育相关,表明症状与正规教育之间存在相互作用。阴性症状与连接性独立相关,但与情绪词无关,尽管与教育的关联是相互依存的。教育和症状共同解释了近 70%的连接性变异(R:0.67,p<0.0001),而不是情绪表达。在精神病的初始阶段,教育似乎起着重要作用,减轻了阴性症状对叙事连接性的影响。FEP 中的阴性症状与情绪表达相关联,影响叙事连接性,通过简短而无害的协议揭示了社会认知的方面。

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