Shaban Nader, Hoad Caroline L, Naim Iyad, Alshammari Meshari, Radford Shellie Jean, Clarke Christopher, Marciani Luca, Moran Gordon
NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.
NIHR Nottingham Biomedical Research Centre, University of Nottingham University Park Campus, Nottingham, UK.
Frontline Gastroenterol. 2022 Jun 2;13(e1):e28-e34. doi: 10.1136/flgastro-2022-102117. eCollection 2022.
The use of cross-sectional imaging and ultrasonography has long complemented endoscopic assessment of inflammatory bowel disease (IBD). Clinical symptoms alone are often not enough to assess disease activity, so a reliance on non-invasive techniques is essential. In this paper, we aim to examine the current use of radiological modalities in aiding the management of patients with IBD. We focus on the various sections of the gastrointestinal tract and how different modalities can aid in assessing current disease state and response to treatments. We also have a look at how newer sequences in cross-sectional imaging and ultrasonography can allow for better differentiation of disease activity (ie, fibrotic vs inflammatory) as well improve evaluation of small bowel, colonic and perianal disease. Furthermore, we examine how advanced image processing has the potential to allow radiology to be a surrogate for biomarkers. An example of this is explored when reviewing the ability of MR sequences to quantify visceral fat, which potentially plays a role in determining disease activity in Crohn's disease. Lastly, we look into the expected role for artificial intelligence to be used as an adjunct to radiology to better improve IBD evaluation.
横断面成像和超声检查的应用长期以来一直是对炎症性肠病（IBD）进行内镜评估的补充。仅靠临床症状往往不足以评估疾病活动度，因此依赖非侵入性技术至关重要。在本文中，我们旨在探讨放射学检查方法目前在辅助IBD患者管理方面的应用。我们关注胃肠道的各个部分，以及不同的检查方法如何有助于评估当前的疾病状态和对治疗的反应。我们还将探讨横断面成像和超声检查中更新的序列如何能够更好地区分疾病活动度（即纤维化与炎症），以及如何改善对小肠、结肠和肛周疾病的评估。此外，我们研究先进的图像处理如何有可能使放射学成为生物标志物的替代方法。在回顾磁共振序列量化内脏脂肪的能力时探讨了这方面的一个例子，内脏脂肪可能在确定克罗恩病的疾病活动度中起作用。最后，我们研究人工智能作为放射学辅助手段以更好地改善IBD评估的预期作用。
