Yin Jing, Zheng Mo
Department of Pathology, The Fifth Central Hospital of Tianjin, Binhai New Area, Tianjin 300450, China.
World J Clin Cases. 2022 Jun 6;10(16):5428-5434. doi: 10.12998/wjcc.v10.i16.5428.
There is limited information on ipsilateral synchronous papillary renal cell carcinoma (PRCC) and clear cell renal cell carcinoma (CCRCC). Therefore, these rare tumors are often misdiagnosed preoperatively as a single tumor with intrarenal metastasis or some other diseases. Effective management and long-term overall survival might be affected because the prognosis of the two tumors differs.
We describe a case of ipsilateral synchronous PRCC and CCRCC with two histological variants in a 72-year-old man, whose mass was found incidentally, with no other chief complaints and vital signs were normal. Initial ultrasound revealed a hypoechoic lobular mass with a volume of 7.8 cm × 4.8 cm × 2.8 cm in the middle to lower pole of the left kidney. A subsequent contrast-enhanced computed tomography scan showed a single endophytic mass of 7.5 cm in diameter. The patient underwent laparoscopic left radical nephrectomy. A final diagnosis of ipsilateral synchronous PRCC and CCRCC was confirmed by pathological examination. There was no recurrence or metastasis after 25 mo follow-up.
We report a case of ipsilateral synchronous PRCC and CCRCC, and review related literature to estimate the prevalence of similar cases. The above descriptions may be expected to help understand the disease, and improve diagnosis in the future.
关于同侧同步性乳头状肾细胞癌（PRCC）和透明细胞肾细胞癌（CCRCC）的信息有限。因此，这些罕见肿瘤术前常被误诊为单一肿瘤伴肾内转移或其他疾病。由于这两种肿瘤的预后不同，可能会影响有效的治疗和长期总生存期。
我们描述了一例72岁男性同侧同步性PRCC和CCRCC病例，该患者有两种组织学变体，肿块为偶然发现，无其他主要主诉，生命体征正常。最初的超声检查显示左肾中下级有一个低回声小叶肿块，体积为7.8 cm×4.8 cm×2.8 cm。随后的增强计算机断层扫描显示一个直径7.5 cm的单发内生性肿块。患者接受了腹腔镜下左肾根治性切除术。病理检查确诊为同侧同步性PRCC和CCRCC。随访25个月后无复发或转移。
我们报告了一例同侧同步性PRCC和CCRCC病例，并回顾相关文献以评估类似病例的发生率。上述描述可能有助于了解该疾病，并在未来改善诊断。
