Ural State Medical University of the Ministry of Health of the Russian Federation, Ekaterinburg, Russia.
Future Cardiol. 2022 Sep;18(9):719-729. doi: 10.2217/fca-2021-0066. Epub 2022 Jul 11.
Determining the optimal prescribing and stopping points for diuretic therapy remains a challenge in outpatients who have heart failure with preserved ejection fraction. The aim was to study pulmonary vein diameters for prescribing diuretic therapy and estimating its effectiveness in outpatients with heart failure with preserved ejection fraction. Patients with heart failure with preserved ejection fraction were examined before and after 6 months of standard heart failure therapy, including loop diuretics. The maximum and minimum diameters of pulmonary veins were estimated by echocardiography. A decrease in the maximum and minimum diameters of the pulmonary vein and the left atrial volume was detected after treatment. Increases in pulmonary vein diameters and left atrial volumes in the absence of symptoms and signs of heart failure were detected after withdrawing diuretic therapy; this caused its resumption in a maintenance dose. Pulmonary vein diameters can be used for prescribing diuretic therapy and estimating its effectiveness in outpatients with heart failure with preserved ejection fraction.
确定心力衰竭伴射血分数保留患者门诊患者利尿剂治疗的最佳起始和停药点仍然是一项挑战。本研究旨在通过超声心动图检测肺静脉直径来指导利尿剂治疗，并评估其对心力衰竭伴射血分数保留患者的疗效。心力衰竭伴射血分数保留患者在接受标准心力衰竭治疗 6 个月前后，包括袢利尿剂，进行检查。通过超声心动图评估肺静脉的最大和最小直径。治疗后检测到最大和最小肺静脉直径以及左心房容积减小。在没有心力衰竭症状和体征的情况下，撤去利尿剂后，发现肺静脉直径和左心房容积增加；这导致其以维持剂量重新开始。肺静脉直径可用于指导心力衰竭伴射血分数保留患者的利尿剂治疗，并评估其疗效。
