Micrococcin P2 Targets .

infection is a global public health threat. Extensive assays using clinical isolates have identified micrococcin P2 (MP2, ) as a particularly effective anti- agent. MP2 possesses a mode of action that differs from other antibiotics and pharmacokinetic properties that render it especially promising. Its time-kill studies have been investigated using hypervirulent ribotype 027. DSS (dextran sulfate sodium)-induced mouse studies with that strain indicate that is better than vancomycin and fidaxomicin. Thus, micrococcin P2 is a valuable platform to be exploited for the development of new anti- antibiotics.