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经双向内镜入路行 R0 阴道残端复发妇科恶性肿瘤切除术:四例患者的病例系列。

R0 resection of vaginal stump recurrence of gynecologic malignancy by bi-directional endoscopic approach: A case series of four patients.

机构信息

Department of Obstetrics and Gynecology, Kansai Medical University, Osaka, Japan.

出版信息

Asian J Endosc Surg. 2023 Jan;16(1):82-85. doi: 10.1111/ases.13100. Epub 2022 Jul 11.

DOI:10.1111/ases.13100
PMID:35817422
Abstract

Vaginal stump recurrence post-hysterectomy for gynecologic malignancies occurs in 2%-3% of cases. Local excision has been recognized as the primary treatment of localized recurrence, in which precise surgical margin is critical. However, R0 resection is not always easy, given the deep and narrow operation field, as well as severe postoperative fibrosis or adhesion of the vaginal stump at times. Here, we report four cases of vaginal stump recurrence of gynecologic malignancies resected by bi-directional (laparoscopic and pneumovaginoscopic) endoscopy to overcome these difficulties. The primary tumors were uterine cancer in two cases and uterine cervical and ovarian cancer in one case each. The mean operating time was 199 (162-235) minutes, blood loss was minimal, and no perioperative complications were observed. Postoperative follow-up (7.0-19.4 months) revealed no recurrence. This combined procedure could be a therapeutic option for localized vaginal stump recurrence.

摘要

妇科恶性肿瘤子宫切除术后阴道残端复发的发生率为 2%-3%。局部切除术已被公认为局部复发的主要治疗方法,其中精确的手术切缘至关重要。然而,由于手术部位深而狭窄,以及阴道残端有时严重的术后纤维化或粘连,R0 切除并不总是容易的。在此,我们报告了 4 例妇科恶性肿瘤阴道残端复发的病例,这些病例通过双向(腹腔镜和经阴道气腹镜)内镜切除来克服这些困难。原发性肿瘤分别为子宫癌 2 例,子宫颈癌和卵巢癌各 1 例。平均手术时间为 199(162-235)分钟,出血量少,无围手术期并发症。术后随访(7.0-19.4 个月)未见复发。这种联合手术可能是治疗局限性阴道残端复发的一种选择。

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引用本文的文献

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Pneumovaginoscopy-assisted radical hysterectomy for early-stage cervical cancer: a novel bidirectional approach for tumor spillage prevention and R0 resection.经阴道镜辅助根治性子宫切除术治疗早期宫颈癌:一种新型的预防肿瘤播散和实现 R0 切除的双向方法。
J Gynecol Oncol. 2023 Nov;34(6):e80. doi: 10.3802/jgo.2023.34.e80. Epub 2023 Jul 6.
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Fertility-sparing radical resection of juvenile clear cell adenocarcinoma of the cervix by pneumovaginal endoscopic surgery.经阴道充气内镜手术对宫颈幼年型透明细胞腺癌进行保留生育功能的根治性切除术。
Gynecol Oncol Rep. 2023 Jan 18;45:101135. doi: 10.1016/j.gore.2023.101135. eCollection 2023 Feb.