Montgomery P A, Patton S, Huston G E, Josephson R V
Comp Biochem Physiol B. 1987;86(4):635-9. doi: 10.1016/0305-0491(87)90202-1.
Protein patterns of skim milk and fat globule phases were relatively unchanging throughout 9 months lactation, the only notable differences being a rise in lysozyme and a decline up to 6 months with increase thereafter in lactoferrin. Profound changes in protein patterns of the breast secretion were observed during the first week postpartum. True colostrum, in which peptides of sIgA dominate the protein patterns, exists for at most the 2 initial days of secretion. Proteins of mature milk are not coordinated to appear in the colostral secretion simultaneously. A band corresponding to alpha-lactalbumin is present from the initial secretion; that for beta-casein emerges approximately 2 days layer.
在整个9个月的哺乳期，脱脂乳和脂肪球相的蛋白质模式相对不变，唯一显著的差异是溶菌酶增加，乳铁蛋白在6个月前下降，之后增加。产后第一周观察到乳腺分泌物的蛋白质模式发生了深刻变化。真正的初乳，其中分泌型免疫球蛋白A的肽在蛋白质模式中占主导地位，最多存在于分泌的最初2天。成熟乳的蛋白质并非同时在初乳分泌中出现。从最初分泌就存在一条对应于α-乳白蛋白的条带；β-酪蛋白的条带大约在2天后出现。
