Rubin R, Georgi M, Kissler W, Rumpelt H J, Schulz V
Prax Klin Pneumol. 1978 Sep;32(9):598-612.
It were Liebow et al. (1965) who, for the first time, described the desquamative interstitial pneumonia (DIP) as one clinical and morphological unit. The etiopathology of this disease is still unknown and there exist many controversial opinions as to its role within the interstitial pneumonias. For the clinical-physician the DIP represents a difficult problem because there seems to be no uniform appearance to this disease. So a lung-biopsy is the unique way to make a definitive diagnosis. The following description represents a case of DIP observed at our hospital. At the same time we tried to give a review of our present knowledge concerning the morphology, course and therapy of this disease. We think it should be note that the DIP was accompanied by an extreme peripheral eosinophilia. To our knowledge this is the first time such a phenomenon is described. In the course of the treatment with steroids the eosinophilia disappeared parallel to the normalization of the radiographic findings.
是利博等人（1965年）首次将脱屑性间质性肺炎（DIP）描述为一个临床和形态学单位。这种疾病的病因病理仍然未知，关于其在间质性肺炎中的作用存在许多有争议的观点。对于临床医生来说，DIP是一个难题，因为这种疾病似乎没有统一的表现。因此，肺活检是做出明确诊断的唯一方法。以下描述是我们医院观察到的一例DIP病例。同时，我们试图对目前关于这种疾病的形态学、病程和治疗的知识进行综述。我们认为应该注意到，DIP伴有外周血嗜酸性粒细胞极度增多。据我们所知，这是首次描述这种现象。在使用类固醇治疗的过程中，嗜酸性粒细胞增多症随着影像学表现的正常化而消失。
