Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Aging Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
J Am Med Inform Assoc. 2022 Aug 16;29(9):1497-1507. doi: 10.1093/jamia/ocac111.
The purpose of the study was to develop and validate a model to predict the risk of experiencing a fall for nursing home residents utilizing data that are electronically available at the more than 15 000 facilities in the United States.
The fall prediction model was built and tested using 2 extracts of data (2011 through 2013 and 2016 through 2018) from the Long-term Care Minimum Dataset (MDS) combined with drug data from 5 skilled nursing facilities. The model was created using a hybrid Classification and Regression Tree (CART)-logistic approach.
The combined dataset consisted of 3985 residents with mean age of 77 years and 64% female. The model's area under the ROC curve was 0.668 (95% confidence interval: 0.643-0.693) on the validation subsample of the merged data.
Inspection of the model showed that antidepressant medications have a significant protective association where the resident has a fall history prior to admission, requires assistance to balance while walking, and some functional range of motion impairment in the lower body; even if the patient exhibits behavioral issues, unstable behaviors, and/or are exposed to multiple psychotropic drugs.
The novel hybrid CART-logit algorithm is an advance over the 22 fall risk assessment tools previously evaluated in the nursing home setting because it has a better performance characteristic for the fall prediction window of ≤90 days and it is the only model designed to use features that are easily obtainable at nearly every facility in the United States.
本研究旨在开发和验证一种模型,以利用美国 15000 多家机构提供的电子数据,预测养老院居民发生跌倒的风险。
使用来自长期护理最低数据集(MDS)的 2 个数据提取(2011 年至 2013 年和 2016 年至 2018 年)以及来自 5 家熟练护理设施的药物数据,结合构建和测试跌倒预测模型。该模型使用混合分类和回归树(CART)-逻辑方法创建。
合并数据集包括 3985 名年龄平均为 77 岁、64%为女性的居民。该模型在合并数据的验证子样本中的 ROC 曲线下面积为 0.668(95%置信区间:0.643-0.693)。
对模型的检查表明,抗抑郁药物具有显著的保护作用,即居民在入院前有跌倒史、在行走时需要帮助保持平衡以及下肢有一定的功能活动范围受损;即使患者表现出行为问题、不稳定行为和/或接触多种精神药物。
新的混合 CART-逻辑算法是对以前在养老院环境中评估的 22 种跌倒风险评估工具的一项进步,因为它在≤90 天的跌倒预测窗口中具有更好的性能特征,而且它是唯一设计用于使用几乎在美国每家机构都能轻松获得的功能的模型。