van Delft J L, van Haeringen N J, Glasius E, Barthen E R, Oosterhuis J A
Curr Eye Res. 1987 Mar;6(3):419-25. doi: 10.3109/02713688709025197.
Aqueous protein content was estimated as a measure of the integrity of the blood-aqueous barrier after paracentesis or argon laser photo-coagulation of the iris in rabbits. Corticosteroid pretreatment topically or by subconjunctival or intramuscular injection exerted only a moderate inhibitory effect on the breakdown of the blood-aqueous barrier. Instillation of 0.1% indomethacin however, strongly inhibited the response in both models. The results are indicative of the potential usefulness of topical administration of prostaglandin synthetase inhibitors in the treatment of non-infectious inflammatory diseases.
