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pCONUS2 和 pCONUS2 HPC 颈桥接装置:一项国际多中心回顾性研究的结果。

The pCONUS2 and pCONUS2 HPC Neck Bridging Devices : Results from an International Multicenter Retrospective Study.

机构信息

Department of Neuroradiology, Hospital Universitari i Politècnic La Fe, València, Spain.

Department of Radiology, Hospital Universitari La Ribera, Alzira, Spain.

出版信息

Clin Neuroradiol. 2023 Mar;33(1):129-136. doi: 10.1007/s00062-022-01191-w. Epub 2022 Jul 11.

Abstract

INTRODUCTION

Bifurcation aneurysms represent an ongoing endovascular challenge with a variety of techniques and devices designed to address them. We present our multicenter series of the pCONUS2 and pCONUS2 HPC devices when treating bifurcation aneurysms.

METHODS

We performed a retrospective review of our prospectively maintained databases at 3 tertiary neurointerventional centers to identify all patients who underwent coil embolization with the pCONUS2 or pCONUS2 HPC device between February 2015 and August 2021. We recorded baseline demographics, aneurysm data, complications, immediate and delayed angiographic results.

RESULTS

We identified 55 patients with 56 aneurysms, median age 63 years (range 42-78 years), 67.3% female (n = 37). The commonest aneurysm location was the MCA bifurcation (n = 40, 71.4%). Average dome height was 8.9 ± 4.2 mm (range 3.2-21.5 mm), average neck width 6.4 ± 2.5 mm (range 2.6-14 mm), and average aspect ratio 1.3 ± 0.6 (range 0.5-3.3). The pCONUS2 was used in 64.3% and the pCONUS2 HPC in 35.7%. The procedural technical success rate was 98.2%. Intraoperative complications occurred in 5 cases (8.9%), 4 of which were related to the coils with partial thrombus formation on the pCONUS2 HPC seen in 1 case that was resolved with heparin. In relation to the procedure and treatment of the aneurysm the overall permanent morbidity was 1.8% (n = 1/55) and mortality 0%. Delayed angiographic follow-up (48 aneurysms) at median 12 months postprocedure (range 3-36 months) demonstrated adequate occlusion of 83.4% of aneurysms.

CONCLUSION

The pCONUS2 and pCONUS2 HPC devices carry a high technical success rate, low complication and retreatment rate, and good rates of adequate occlusion. Larger prospective confirmatory studies are required.

摘要

简介

分支动脉瘤是一种持续存在的血管内挑战,有各种旨在解决这些问题的技术和设备。我们介绍了我们在 3 个三级神经介入中心进行的多中心 pCONUS2 和 pCONUS2 HPC 装置治疗分支动脉瘤的系列研究。

方法

我们对 3 个三级神经介入中心前瞻性维护的数据库进行了回顾性分析,以确定 2015 年 2 月至 2021 年 8 月期间接受 pCONUS2 或 pCONUS2 HPC 装置线圈栓塞治疗的所有患者。我们记录了基线人口统计学、动脉瘤数据、并发症、即刻和延迟血管造影结果。

结果

我们确定了 55 例 56 个动脉瘤患者,中位年龄 63 岁(范围 42-78 岁),女性占 67.3%(n=37)。最常见的动脉瘤部位是 MCA 分叉(n=40,71.4%)。平均瘤顶高度为 8.9±4.2mm(范围 3.2-21.5mm),平均颈部宽度为 6.4±2.5mm(范围 2.6-14mm),平均纵横比为 1.3±0.6(范围 0.5-3.3)。pCONUS2 用于 64.3%,pCONUS2 HPC 用于 35.7%。手术技术成功率为 98.2%。术中并发症发生 5 例(8.9%),其中 4 例与线圈有关,1 例 pCONUS2 HPC 线圈上有部分血栓形成,用肝素解决。与手术过程和动脉瘤治疗有关的总永久性发病率为 1.8%(n=55),死亡率为 0%。术后中位数 12 个月(范围 3-36 个月)的延迟血管造影随访显示,83.4%的动脉瘤得到充分闭塞。

结论

pCONUS2 和 pCONUS2 HPC 装置具有较高的技术成功率、较低的并发症和再治疗率,以及良好的充分闭塞率。需要更大规模的前瞻性确认性研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79d3/10014770/38a79355b2ce/62_2022_1191_Fig1_HTML.jpg

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