Liu H M
Chin J Physiol. 1986;29(2):65-9.
The effect of swimming-stress on pain threshold was investigated in normal and hypophysectomized male rats of Long-Evans strain. The Tail-Flick Latency (TFL) was taken for determining the algesic sensitivity to noxious heat stimulation of the tail. The present study has shown that swimming-stress could prolong the TFL to thermal tail stimulation. In 15 intact control rats, the TFL were prolonged from 2.47 +/- 0.07 (Mean +/- S.E.) to 3.81 +/- 0.21 sec. In 10 sham-operated and 10 hypophysectomized rats, the TFL were also prolonged from 3.10 +/- 0.25 to 4.37 +/- 0.35 and 3.59 +/- 0.09 to 4.50 +/- 0.13 sec respectively after a 3 min swim. Therefore, the hypophysectomy did not appear to modulate the analgesic effect induced by swimming-stress. These experimental data implied that the hypophysis may not be important in the analgesic effect induced by the swimming-stress.
在Long-Evans品系的正常和垂体切除雄性大鼠中，研究了游泳应激对痛阈的影响。采用甩尾潜伏期（TFL）来确定对尾部有害热刺激的痛觉敏感性。本研究表明，游泳应激可延长对热尾刺激的TFL。在15只完整对照大鼠中，TFL从2.47±0.07（平均值±标准误）延长至3.81±0.21秒。在10只假手术大鼠和10只垂体切除大鼠中，游泳3分钟后，TFL也分别从3.10±0.25延长至4.37±0.35，从3.59±0.09延长至4.50±0.13秒。因此，垂体切除似乎并未调节游泳应激诱导的镇痛作用。这些实验数据表明，垂体在游泳应激诱导的镇痛作用中可能并不重要。
