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婴儿黑色素性神经外胚层肿瘤:免疫组织化学分析的应用

Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis.

作者信息

de Sousa André Luca Araujo, de Almeida Wanderson Carvalho, de Pinho Mendes Jean, Martins Montalli Victor Angelo, Pinto Antonione Santos Bezerra

机构信息

Dentistry Course, State University of Piauí, Brazil, ORCID: https://orcid.org/0000-0003-4876-9188.

Dentistry Course, State University of Piauí, Brazil, ORCID: https://orcid.org/0000-0001-5889-5490.

出版信息

Acta Stomatol Croat. 2022 Jun;56(2):176-182. doi: 10.15644/asc56/2/9.

Abstract

The Melanotic Neuroectodermal Tumor of Infancy (MNTI) is an asymptomatic, pigmented neoplasm characterized by a fast and locally aggressive growth along with a rare tissue formation. In the diagnostic process, the use of imaging exams can suggest a local destruction suggestive of malignancy, a sign of bone remodeling and expansion. Therefore, as any early diagnosis minimizes risks and improves the prognosis of treatment for the patient, the aim of this study was, based on a clinical case report, to corroborate the use of histopathological analysis associated with immunohistochemistry. Thus, we conclude that the immunohistochemical exam is of great importance for a better complementation of the MNTI diagnosis process. In addition, it can reveal signs of possible aggressive growth.

摘要

婴儿黑色素性神经外胚层肿瘤(MNTI)是一种无症状的色素性肿瘤,其特征是生长迅速且局部侵袭性强,伴有罕见的组织形成。在诊断过程中,影像学检查的结果可能提示局部破坏,这暗示着恶性肿瘤,同时也是骨重塑和扩张的迹象。因此,由于任何早期诊断都能将风险降至最低并改善患者的治疗预后,本研究的目的是基于一例临床病例报告,证实组织病理学分析与免疫组织化学相结合的应用。因此,我们得出结论,免疫组织化学检查对于更好地完善MNTI诊断过程非常重要。此外,它还可以揭示可能的侵袭性生长迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49c5/9262114/edc97476023f/ASC_56(2)_176-182-f1.jpg

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