de Sousa André Luca Araujo, de Almeida Wanderson Carvalho, de Pinho Mendes Jean, Martins Montalli Victor Angelo, Pinto Antonione Santos Bezerra
Dentistry Course, State University of Piauí, Brazil, ORCID: https://orcid.org/0000-0003-4876-9188.
Dentistry Course, State University of Piauí, Brazil, ORCID: https://orcid.org/0000-0001-5889-5490.
Acta Stomatol Croat. 2022 Jun;56(2):176-182. doi: 10.15644/asc56/2/9.
The Melanotic Neuroectodermal Tumor of Infancy (MNTI) is an asymptomatic, pigmented neoplasm characterized by a fast and locally aggressive growth along with a rare tissue formation. In the diagnostic process, the use of imaging exams can suggest a local destruction suggestive of malignancy, a sign of bone remodeling and expansion. Therefore, as any early diagnosis minimizes risks and improves the prognosis of treatment for the patient, the aim of this study was, based on a clinical case report, to corroborate the use of histopathological analysis associated with immunohistochemistry. Thus, we conclude that the immunohistochemical exam is of great importance for a better complementation of the MNTI diagnosis process. In addition, it can reveal signs of possible aggressive growth.
婴儿黑色素性神经外胚层肿瘤(MNTI)是一种无症状的色素性肿瘤,其特征是生长迅速且局部侵袭性强,伴有罕见的组织形成。在诊断过程中,影像学检查的结果可能提示局部破坏,这暗示着恶性肿瘤,同时也是骨重塑和扩张的迹象。因此,由于任何早期诊断都能将风险降至最低并改善患者的治疗预后,本研究的目的是基于一例临床病例报告,证实组织病理学分析与免疫组织化学相结合的应用。因此,我们得出结论,免疫组织化学检查对于更好地完善MNTI诊断过程非常重要。此外,它还可以揭示可能的侵袭性生长迹象。