Halfon S T, Tamir D, Bronner S
Eur J Epidemiol. 1987 Mar;3(1):39-45. doi: 10.1007/BF00145071.
The determinants of blood pressure level were analyzed in a group of 1154 Jerusalem school children aged 12. After controlling for age, significant differences in blood pressure measurements were found between three groups: boys, pre-menarche girls and post-menarche girls. A comparison of the means of selected biological variables showed that girls who have reached menarche have levels of systolic blood pressure, weight, height and Quetelet's index higher than boys and pre-menarche girls. However, levels of triceps skinfold thickness and pulse rate were similar in the two groups of girls and higher than in boys. Using multiple regression analysis, we found that much of the variance (boys 29%, post-menarche girls 21% and pre-menarche girls 15%) of systolic blood pressure could be explained by a combination of biological variables (Quetelet, pulse rate, triceps skinfold thickness and height) while these variables explained a much smaller proportion (boys 12%, post-menarche girls 17% and pre-menarche 9%) of diastolic blood pressure variance. The predictive power of systolic blood pressure by the measured biological variables was higher in boys than in girls. However, diastolic blood pressure was better predicted by the biological variables in the group of girls with menarche than in other groups. Elevated blood pressure was observed in 3.2% of the examined children. High values for Quetelet's index were observed in 6.4%. The prevalence of elevated measurements of blood pressure and Quetelet's index were significantly higher in girls with menarche. Among children aged 12, the association between sociodemographic characteristics and blood pressure level was weak, as measured in multiple regression analysis.
对1154名12岁的耶路撒冷学童的血压水平决定因素进行了分析。在控制年龄后,发现三组之间的血压测量存在显著差异:男孩、月经初潮前女孩和月经初潮后女孩。对选定生物变量均值的比较表明,已达到月经初潮的女孩的收缩压、体重、身高和奎特利指数水平高于男孩和月经初潮前女孩。然而,两组女孩的肱三头肌皮褶厚度和脉搏率水平相似且高于男孩。使用多元回归分析,我们发现收缩压的大部分方差(男孩为29%,月经初潮后女孩为21%,月经初潮前女孩为15%)可以由生物变量(奎特利指数、脉搏率、肱三头肌皮褶厚度和身高)的组合来解释,而这些变量对舒张压方差的解释比例要小得多(男孩为12%,月经初潮后女孩为17%,月经初潮前女孩为9%)。测量的生物变量对男孩收缩压的预测能力高于女孩。然而,月经初潮女孩组中生物变量对舒张压的预测效果优于其他组。在3.2%的受检儿童中观察到血压升高。在6.4%的儿童中观察到奎特利指数值较高。月经初潮女孩中血压和奎特利指数测量值升高的患病率显著更高。在12岁的儿童中,如多元回归分析所示,社会人口学特征与血压水平之间的关联较弱。