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经导管主动脉瓣置换术后退伍军人与非退伍军人结局的直接比较:使用经导管瓣膜治疗登记研究。

Direct Comparison of Outcomes After Transcatheter Aortic Valve Replacement in Veterans and Non-Veterans Using the Transcatheter Valve Therapy Registry.

机构信息

Medical Faculty Associates, The George Washington University, 2150 Pennsylvania Ave NW, Suite 4-417, Washington, DC USA.

出版信息

J Invasive Cardiol. 2022 Aug;34(8):E601-E610. doi: 10.25270/jic/21.00377. Epub 2022 Jul 7.

DOI:10.25270/jic/21.00377
PMID:35830359
Abstract

OBJECTIVES

This study aims to compare veterans and non-veterans undergoing transcatheter aortic valve replacement (TAVR) using data from the Society for Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy (STS/ACC TVT) registry.

METHODS

Patients undergoing TAVR at George Washington University (GWU) and veterans treated at Washington DC Veterans Affairs Medical Center (VAMC) who underwent TAVR at GWU from 2014-2020 were included. All patients were reported in the TVT registry. Emergency and valve-in-valve TAVR were excluded. Cohorts were divided based on veteran status. Operators were the same for both groups. Outcomes were compared at 30 days and 1 year. The primary outcome was mortality and secondary outcomes were morbidity metrics.

RESULTS

A total of 299 patients (91 veterans, 208 non-veterans) were included. Veterans had higher rates of hypertension (87.9% vs 77.9%; P=.04), diabetes (46.7% vs 28.9%; P<.01), and lung disease (2.4% vs 11.0%; P<.001). Outcomes were not significantly different between veterans and non-veterans, including 30-day mortality (0% vs 2.9%, respectively; P=.18), 1-year mortality (9.8% vs 10.7%, respectively; P=.61), stroke incidence (0% vs 2.5%, respectively; P=.73), median intensive care unit stay (24 hours in both groups), and overall hospital stay (2 days in both groups).

CONCLUSIONS

The affiliation between a VAMC and an academic medical center allowed for direct comparison between veterans and non-veterans undergoing TAVR by the same operators using the TVT registry. Despite significantly higher rates of comorbidities, veterans had equivalent outcomes compared with non-veterans. This may be in part due to the comprehensive care that veterans receive in the VAMC and this institution's integrated heart center team.

摘要

目的

本研究旨在利用胸外科医师学会/美国心脏病学会经导管瓣膜治疗(STS/ACC TVT)登记处的数据,比较接受经导管主动脉瓣置换术(TAVR)的退伍军人和非退伍军人。

方法

纳入 2014 年至 2020 年期间在乔治华盛顿大学(GWU)接受 TAVR 的患者和在 GWU 接受 TAVR 的在华盛顿特区退伍军人事务医疗中心(VAMC)治疗的退伍军人,所有患者均在 TVT 登记处报告。排除紧急情况和瓣中瓣 TAVR。根据退伍军人身份将队列分为两组。两组的手术医生相同。在 30 天和 1 年时比较结果。主要结果是死亡率,次要结果是发病率指标。

结果

共纳入 299 例患者(91 例退伍军人,208 例非退伍军人)。退伍军人的高血压(87.9% vs 77.9%;P=.04)、糖尿病(46.7% vs 28.9%;P<.01)和肺部疾病(2.4% vs 11.0%;P<.001)发生率较高。退伍军人和非退伍军人之间的结果无显著差异,包括 30 天死亡率(分别为 0%和 2.9%;P=.18)、1 年死亡率(分别为 9.8%和 10.7%;P=.61)、卒中发生率(分别为 0%和 2.5%;P=.73)、重症监护病房中位数住院时间(两组均为 24 小时)和总住院时间(两组均为 2 天)。

结论

VAMC 与学术医疗中心的合作关系,使得在 TVT 登记处,由同一手术医生对退伍军人和非退伍军人进行 TAVR 治疗,可进行直接比较。尽管退伍军人的合并症发生率明显较高,但退伍军人的结果与非退伍军人相当。这可能部分归因于退伍军人在 VAMC 接受的全面护理,以及该机构综合心脏中心团队的作用。

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