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[霍顿氏病。当前问题]

[Horton's disease. Current problems].

作者信息

Godeau P, Bletry O, Garin J L, Herreman G, Wechsler B, Guillevin L

出版信息

Sem Hop. 1979;55(7-8):347-53.

PMID:35832
Abstract

Much that has been written in the last few years concerning temporal arteritis has allowed us to better clarify the clinical picture, and for example frequency of hepatic involvement. The atypical forms of the disease such as those that involves large arteries, or those in which sedimentation rate is normal, are better known. It is in such atypical cases, particularly in a young patient, that an external carotid arteriography is most useful. Though the pathophysiology of the disease is not well understood, serologic and histologic arguments exist in favor of an autoimmune etiology, in which the antigen would be the alestin, found in the internal elastic lamina of the artery. Temporal arteritis is theorically well classified amongst the giant cell granulomatous arterities but there are some atypical forms difficult to distinguish from Takayasu's arteritis or even periarteritis nodosa.

摘要

在过去几年里,许多关于颞动脉炎的文献让我们能够更好地阐明其临床表现,例如肝脏受累的频率。该疾病的非典型形式,如累及大动脉的形式或血沉正常的形式,已为人所知。正是在这种非典型病例中,尤其是年轻患者,颈外动脉造影最为有用。尽管该疾病的病理生理学尚未完全了解,但血清学和组织学证据支持自身免疫病因,其中抗原可能是在动脉内弹性膜中发现的弹力素。理论上,颞动脉炎在巨细胞肉芽肿性动脉炎中分类明确,但仍有一些非典型形式难以与高安动脉炎甚至结节性多动脉炎区分开来。

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