Department of Gastroenterology and Hepatology, Antwerp University Hospital, Antwerp, Belgium.
Department of General Internal Medicine, Infectious Diseases and Tropical Medicine, Antwerp University Hospital, Antwerp, Belgium.
Acta Gastroenterol Belg. 2022 Jul-Sep;85(3):518-521. doi: 10.51821/85.3.8934. Epub 2022 Jun 30.
Acute pancreatitis can be complicated with necrosis of the pancreatic or peripancreatic tissue. This necrosis can become liquified and form a well-defined wall (walled-off necrosis or WON) and can become infected and form abscesses. Necrotizing soft tissue infections are rare infections of the deep tissue and subcutaneous fat and are mostly caused by trauma or perforated visceral organs. They can, however, rarely be caused by infected retroperitoneal collections. To date only 3 case reports have been published of a necrotizing soft tissue infection complicating a necrotizing pancreatitis. Both acute, complicated pancreatitis and necrotizing soft tissue infections carry a high mortality and morbidity rate with surgery being the mainstay therapy for the latter, often leaving the patient disfigured. We report the case of a 62-year-old man presenting to the emergency department with a painful and erythematous rash of the upper leg as complication of an acute necrotizing pancreatitis.
急性胰腺炎可并发胰腺或胰周组织坏死。这种坏死可以液化并形成明确的壁(包裹性坏死或 WON),并可能感染形成脓肿。坏死性软组织感染是深部组织和皮下脂肪的罕见感染,主要由创伤或穿孔的内脏器官引起。然而,它们很少由感染的腹膜后积液引起。迄今为止,仅有 3 例报告了并发坏死性胰腺炎的坏死性软组织感染。急性、复杂的胰腺炎和坏死性软组织感染都有很高的死亡率和发病率,手术是后者的主要治疗方法,这常常使患者毁容。我们报告了一例 62 岁男性的病例,他因急性坏死性胰腺炎并发大腿疼痛和红斑疹而到急诊就诊。