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加利福尼亚寄养系统中的抗精神病药物:十年分析。

Antipsychotics in the California Foster Care System: A 10-Year Analysis.

机构信息

Stanford Center for Clinical Research, Stanford University, Palo Alto, California, USA.

Department of Social Work, California State University East Bay, Hayward, California, USA.

出版信息

J Child Adolesc Psychopharmacol. 2022 Sep;32(7):400-407. doi: 10.1089/cap.2022.0040. Epub 2022 Jul 14.

Abstract

In response to concerns regarding psychotropic medication prescribing, California's foster care system implemented oversight strategies to improve prescribing and monitoring practice, particularly for antipsychotics. The impact of these policies has not been evaluated. To examine foster youth psychotropic use data in California and their relationship to national and state policy initiatives. This study analyzed 2011-2020 data curated by the California Child Welfare Indicators Project. The platform matches Medicaid medication and laboratory claims with individual-level foster youth data to report rates of dispensed psychotropic medications, authorization status, and metabolic screening. In 2011, there were 78,231 California youth in foster care, of which 10,435 (13.3%) received psychotropics and 5570 (7.1%) antipsychotics. In 2020, of 68,386 foster children, 7172 (12.2%) received psychotropics and 2068 (3.0%) antipsychotics. Proper authorizations for psychotropics were obtained for 5581 (77.8%) foster youth in 2020. Of those receiving antipsychotics, 904 (43.7%) underwent metabolic screening. The greatest declines in antipsychotic use occurred between 2013 (6.7%) and 2018 (3.1%). Overall 2011 to 2020 declines were similar for males (8.5% → 3.6%, 58% reduction,  < 0.001) and females (5.5% → 2.4%, 57% reduction,  < 0.001). Regarding age and race, greater declines occurred for children <10 years (2.33% → 0.84%, 64% reduction,  < 0.001) and Latino youth (5.4% → 2.2%, 59% reduction,  < 0.001). Temporal patterns in antipsychotic use suggest an impact of policies and guidelines. While 12.2% of foster youth continue to receive psychotropics, there were reductions in racial/ethnic disparities and declines in antipsychotic use. Lack of adherence to authorization and metabolic screening requirements continue to be concerning.

摘要

针对精神药物处方问题,加州的寄养系统实施了监督策略,以改善处方和监测实践,尤其是针对抗精神病药物。这些政策的影响尚未得到评估。

本研究分析了 2011 年至 2020 年期间由加州儿童福利指标项目整理的数据。该平台将医疗补助药物和实验室申报与个体寄养青年数据相匹配,以报告发放的精神药物、授权状态和代谢筛查的比例。2011 年,加州有 78231 名青年在寄养中,其中 10435 人(13.3%)接受了精神药物治疗,5570 人(7.1%)接受了抗精神病药物治疗。2020 年,在 68386 名寄养儿童中,7172 人(12.2%)接受了精神药物治疗,2068 人(3.0%)接受了抗精神病药物治疗。2020 年,有 5581 名(77.8%)寄养青年获得了精神药物的适当授权。在接受抗精神病药物治疗的人中,有 904 人(43.7%)接受了代谢筛查。抗精神病药物使用的最大降幅发生在 2013 年(6.7%)至 2018 年(3.1%)之间。总体而言,2011 年至 2020 年期间,男性(8.5%→3.6%,减少 58%,<0.001)和女性(5.5%→2.4%,减少 57%,<0.001)的降幅相似。在年龄和种族方面,10 岁以下儿童的降幅更大(2.33%→0.84%,减少 64%,<0.001)和拉丁裔青年(5.4%→2.2%,减少 59%,<0.001)。抗精神病药物使用的时间模式表明政策和指导方针产生了影响。尽管仍有 12.2%的寄养青年在接受精神药物治疗,但种族/族裔差异有所减少,抗精神病药物的使用也有所下降。不遵守授权和代谢筛查要求的情况仍然令人担忧。

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