Ningbo University of Technology, Zheijang, China; Cardinal Stefan Wyszynski University in Warsaw, Faculty of Mathematical and Natural Sciences, Warszawa, Poland.
Institute of Physical Chemistry, Polish Academy of Sciences, Warszawa, Poland.
Carbohydr Res. 2022 Oct;520:108601. doi: 10.1016/j.carres.2022.108601. Epub 2022 Jun 13.
Crystalline products of vapor diffusion of an alcoholic solution of 1R,4R-camphor into an aqueous solution of α-cyclodextrin were prepared and subjected to X-ray structure analysis. Two different forms were obtained: a dimeric cavity formed by head-to-head association of cyclodextrin (phase A), and a complex set of monomeric cavities (phase B). Both contain camphor molecules orientationally disordered inside cavities. The structures are solvated by mixtures of water and ethanol. The structures significantly differ in chemical stabilities. Whilst phase A is relatively stable with respect to guest desorption, phase B rapidly reacts to change of its chemical environment manifested by cracking of crystals in solution. The phenomenon has been recorded and a short movie is included in the supplementary data.
通过将 1R,4R-樟脑的醇溶液扩散到α-环糊精的水溶液中制备了结晶产物，并对其进行了 X 射线结构分析。得到了两种不同的形式：由环糊精（相 A）头对头缔合形成的二聚体空腔，以及一组单体空腔的复合物（相 B）。这两种形式都包含在空腔内取向无序的樟脑分子。结构由水和乙醇的混合物溶剂化。这些结构在化学稳定性上有显著差异。虽然相 A 相对于客体解吸相对稳定，但相 B 会迅速反应，表现为晶体在溶液中破裂，从而改变其化学环境。这种现象已经被记录下来，并包含在补充数据中的短片中。
