制定基于学校的干预研究预防儿童超重和肥胖的核心结局集：研究方案。

Development of a core outcome set for school-based intervention studies on preventing childhood overweight and obesity: study protocol.

机构信息

Department of Public and Occupational Health, Amsterdam Public Health research institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Psychological Sciences and Health, University of Strathclyde, Glasgow, UK.

出版信息

BMJ Open. 2022 Jul 14;12(7):e051726. doi: 10.1136/bmjopen-2021-051726.

DOI:10.1136/bmjopen-2021-051726

PMID:35835528

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9289030/

Abstract

INTRODUCTION

Prevention of childhood overweight is an important health priority. Evidence synthesis from studies evaluating school-based overweight preventive interventions is hampered by the wealth of different outcomes across studies. Therefore, consensus on a core set of outcomes for school-based overweight prevention studies is needed. .

METHODS AND ANALYSIS

First, a scoping review will be performed to identify outcomes included in studies evaluating school-based overweight prevention interventions in 6-12 year-old children. Additionally, child focus groups will be organised in three countries to list the outcomes children consider important in school-based interventions. Next, an expert panel will identify all unique outcomes (eg, body composition) from the results of the scoping review and focus groups, ruling out how outcomes were defined and measured (eg, body mass index, body fat). In the next phase, a group of international stakeholders will participate in a Delphi study in which they will rate all unique outcomes on a 9-point Likert scale over three rounds to reach consensus on a COS. Participants will include healthcare professionals, policymakers, teachers, school leaders and parents of 6-12 year-olds. All rated outcomes will be presented to stakeholders in two online consensus meetings.

ETHICS AND DISSEMINATION

The Medical Ethics Committee of the VU Medical Center approved the child focus group study in the Netherlands (nr. 2020.071) and the Delphi study-including the consensus meeting (nr. 2022.0295). Other sites will obtain ethics approval for focus groups in their country. The University of Strathclyde School of Psychological Sciences ethics committee approved the Delphi study-including consensus meeting (nr. 72.27.04.2022 .A). The final COS will be disseminated through the diverse networks of all authors and participants.

TRIAL REGISTRATION NUMBER

This COS initiative is registered with the Core Outcome Measures in Effectiveness initiative (registration nr. 971).

摘要

引言

预防儿童超重是一项重要的健康优先事项。评估基于学校的超重预防干预措施的研究中的证据综合受到研究之间大量不同结果的阻碍。因此，需要就基于学校的超重预防研究的核心结果集达成共识。

方法和分析

首先，将进行范围综述，以确定评估 6-12 岁儿童基于学校的超重预防干预措施的研究中包含的结果。此外，将在三个国家组织儿童焦点小组，列出儿童认为基于学校的干预措施中重要的结果。接下来，专家小组将从范围综述和焦点小组的结果中确定所有独特的结果（例如身体成分），排除结果的定义和测量方式（例如体重指数、体脂肪）。在下一阶段，一组国际利益相关者将参与德尔菲研究，他们将在三轮中对所有独特的结果进行 9 分李克特量表评分，以就 COS 达成共识。参与者将包括医疗保健专业人员、政策制定者、教师、学校领导和 6-12 岁儿童的家长。所有评分结果将在两次在线共识会议上呈现给利益相关者。

伦理和传播

VU 医学中心的医学伦理委员会批准了荷兰的儿童焦点小组研究（编号 2020.071）和德尔菲研究-包括共识会议（编号 2022.0295）。其他地点将为其所在国家的焦点小组获得伦理批准。斯特拉斯克莱德大学心理科学学院伦理委员会批准了德尔菲研究-包括共识会议（编号 72.27.04.2022.A）。最终的 COS 将通过所有作者和参与者的多样化网络传播。