一名免疫功能低下的14岁女孩感染人偏肺病毒引发急性心肌炎的首例病例。
First Case of Acute Myocarditis Caused by Metapneumovirus in an Immunocompromised 14-year-old Girl.
作者信息
Makhlouf Anissa, Peipoch Lise, Duport Pauline, Darrieux Etienne, Reguerre Yves, Ramful Duksha, Alessandri Jean-Luc, Levy Yael
机构信息
Department of Pediatric Intensive Care Unit, University Hospital Center La Reunion, Saint-Denis, Ile de La Reunion, France.
Department of Pediatric Oncology, University Hospital Center La Reunion, Saint-Denis, Ile de La Reunion, France.
出版信息
Indian J Crit Care Med. 2022 Jun;26(6):745-747. doi: 10.5005/jp-journals-10071-24255.
BACKGROUND
Human metapneumovirus (hMPV) is a paramyxovirus, well known as a causative agent of respiratory tract infections. Non-respiratory manifestations, including cardiac impairments, remain rare. Only two cases of myocarditis caused by hMPV have been described in adults.
CASE DESCRIPTION
We present the case of a 14-year-old female suffering from Burkitt leukemia and diagnosed with severe myocarditis caused by hMPV, based on results from real-time polymerase chain reaction (RT-PCR) and magnetic resonance imaging (MRI). She was successfully treated by venoarterial extracorporeal membrane oxygenation and intravenous immunoglobulins. She was discharged from pediatric intensive care unit (PICU) 3 weeks later.
CONCLUSION
This is the first pediatric case of hMPV myocarditis requiring venoarterial extracorporeal membrane oxygenation.
HOW TO CITE THIS ARTICLE
Makhlouf A, Peipoch L, Duport P, Darrieux E, Reguerre Y, Ramful D, First Case of Acute Myocarditis Caused by Metapneumovirus in an Immunocompromised 14-year-old Girl. Indian J Crit Care Med 2022;26(6):745-747.
背景
人偏肺病毒（hMPV）是一种副粘病毒，是呼吸道感染的常见病原体。包括心脏损害在内的非呼吸道表现仍然很少见。成人中仅报道过2例由hMPV引起的心肌炎。
病例描述
我们报告了一例14岁患伯基特白血病的女性病例，根据实时聚合酶链反应（RT-PCR）和磁共振成像（MRI）结果，诊断为由hMPV引起的严重心肌炎。她通过静脉-动脉体外膜肺氧合和静脉注射免疫球蛋白成功治愈。3周后她从儿科重症监护病房（PICU）出院。
结论
这是首例需要静脉-动脉体外膜肺氧合治疗的hMPV心肌炎儿科病例。
如何引用本文
Makhlouf A, Peipoch L, Duport P, Darrieux E, Reguerre Y, Ramful D, 免疫功能低下的14岁女孩中首例由偏肺病毒引起的急性心肌炎。《印度危重症医学杂志》2022；26(6):745 - 747。
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