Kwon Joseph, Squires Hazel, Franklin Matthew, Young Tracey
School of Health and Related Research, University of Sheffield, Regent Court (ScHARR), 30 Regent Street, Sheffield, S1 4DA, England, UK.
Cost Eff Resour Alloc. 2022 Jul 16;20(1):33. doi: 10.1186/s12962-022-00367-y.
Falls impose significant health and economic burdens on community-dwelling older persons. Decision modelling can inform commissioning of alternative falls prevention strategies. Several methodological challenges arise when modelling public health interventions including community-based falls prevention. This study aims to conduct a systematic review (SR) to: systematically identify community-based falls prevention economic models; synthesise and critically appraise how the models handled key methodological challenges associated with public health modelling; and suggest areas for further methodological research.
The SR followed the 2021 PRISMA reporting guideline and covered the period 2003-2020 and 12 academic databases and grey literature. The extracted methodological features of included models were synthesised by their relevance to the following challenges: (1) capturing non-health outcomes and societal intervention costs; (2) considering heterogeneity and dynamic complexity; (3) considering theories of human behaviour and implementation; and (4) considering equity issues. The critical appraisal assessed the prevalence of each feature across models, then appraised the methods used to incorporate the feature. The methodological strengths and limitations stated by the modellers were used as indicators of desirable modelling practice and scope for improvement, respectively. The methods were also compared against those suggested in the broader empirical and methodological literature. Areas of further methodological research were suggested based on appraisal results.
46 models were identified. Comprehensive incorporation of non-health outcomes and societal intervention costs was infrequent. The assessments of heterogeneity and dynamic complexity were limited; subgroup delineation was confined primarily to demographics and binary disease/physical status. Few models incorporated heterogeneity in intervention implementation level, efficacy and cost. Few dynamic variables other than age and falls history were incorporated to characterise the trajectories of falls risk and general health/frailty. Intervention sustainability was frequently based on assumptions; few models estimated the economic/health returns from improved implementation. Seven models incorporated ethnicity- and severity-based subgroups but did not estimate the equity-efficiency trade-offs. Sixteen methodological research suggestions were made.
Existing community-based falls prevention models contain methodological limitations spanning four challenge areas relevant for public health modelling. There is scope for further methodological research to inform the development of falls prevention and other public health models.
跌倒给社区居住的老年人带来了重大的健康和经济负担。决策建模可为替代跌倒预防策略的实施提供参考。在对包括基于社区的跌倒预防在内的公共卫生干预措施进行建模时,会出现若干方法学挑战。本研究旨在进行一项系统评价(SR),以:系统识别基于社区的跌倒预防经济模型;综合并批判性评价这些模型如何应对与公共卫生建模相关的关键方法学挑战;并提出进一步方法学研究的领域。
该系统评价遵循2021年PRISMA报告指南,涵盖2003 - 2020年期间以及12个学术数据库和灰色文献。纳入模型的提取方法学特征根据其与以下挑战的相关性进行综合:(1)捕捉非健康结果和社会干预成本;(2)考虑异质性和动态复杂性;(3)考虑人类行为和实施理论;(4)考虑公平问题。批判性评价评估了各特征在模型中的普遍程度,然后评价了纳入该特征所使用的方法。建模者指出的方法学优势和局限性分别用作理想建模实践和改进范围的指标。还将这些方法与更广泛的实证和方法学文献中提出的方法进行了比较。根据评价结果提出了进一步方法学研究的领域。
识别出46个模型。很少有模型全面纳入非健康结果和社会干预成本。对异质性和动态复杂性的评估有限;亚组划分主要限于人口统计学和二元疾病/身体状况。很少有模型在干预实施水平、效果和成本方面纳入异质性。除年龄和跌倒史外,很少纳入其他动态变量来描述跌倒风险和总体健康/虚弱的轨迹。干预的可持续性通常基于假设;很少有模型估计改善实施后的经济/健康回报。七个模型纳入了基于种族和严重程度的亚组,但未估计公平 - 效率权衡。提出了16条方法学研究建议。
现有的基于社区的跌倒预防模型存在方法学局限性,涵盖了与公共卫生建模相关的四个挑战领域。有进一步开展方法学研究的空间,以指导跌倒预防和其他公共卫生模型的开发。