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[翻译文章] 肿瘤整形外科手术中的寡转移。我们的经验。

[Translated article] Oligometastases in oncological orthopaedic surgery. Our experience.

作者信息

Ortiz-Cruz E J, García-Mauriño Peñín C, Moriel-Garceso D J, Peleteiro Pensado M, Barrientos Ruiz I, Redondo Sánchez A, Pozo-Kreilinger J J, Belinchón-Olmeda B, Tapia-Viñe M

机构信息

Servicio de Cirugía Ortopédica y Traumatología, Hospital MD Anderson Cancer Center Madrid, Madrid, Spain; Servicio de Cirugía Ortopédica y Traumatología, Hospital Universitario La Paz, Madrid, Spain.

Servicio de Cirugía Ortopédica y Traumatología, Hospital Universitario La Paz, Madrid, Spain.

出版信息

Rev Esp Cir Ortop Traumatol. 2022 Sep-Oct;66(5):T389-T396. doi: 10.1016/j.recot.2022.07.009. Epub 2022 Jul 14.

Abstract

OBJECTIVE

To analyse the incidence and survival of patients with oligometastases (solitary and normal) when they are treated in centres that are experts in multidisciplinary approach to patients with sarcoma.

MATERIAL AND METHOD

Retrospective analysis of 414 patients with bone metastases secondary to carcinomas at Hospital Universitario La Paz and Hospital MD Anderson Cancer Centre (Madrid) between May 2006 and May 2019. Metastases located in the pelvis and axial skeleton were excluded, analyzing a total of 28 patients who met the criterion for solitary metastases or oligometastases with normal criteria. The study survival estimate was carried out following the Kaplan-Meier statistical method.

RESULTS

The survival of the patients following the oligometastases criteria (solitary and normal) was 53%. Breast cancer was the most prevalent and had a survival rate of more than 70%. The average age of the patients was 58 years old.

DISCUSSION

Systemic treatments in cancer treatment have managed to improve disease-free survival curves and lead us to redirect on the paradigm for the treatment of oligometastases, stating that treatment should be carried out in the centres that are experts in the treatment of sarcomas.

CONCLUSIONS

The choice of surgical treatment for patients with oligometastases in the strict sense (solitary) and normal should be evaluated by multidisciplinary teams according to the prognoses of the patient, anatomical location and histotype of the neoplasm.

摘要

目的

分析寡转移(孤立性且符合正常标准)患者在肉瘤多学科治疗专家中心接受治疗时的发病率和生存率。

材料与方法

对2006年5月至2019年5月期间在拉巴斯大学医院和MD安德森癌症中心(马德里)的414例继发于癌症的骨转移患者进行回顾性分析。排除位于骨盆和中轴骨骼的转移灶,共分析28例符合孤立转移或符合正常标准的寡转移标准的患者。采用Kaplan-Meier统计方法进行研究生存估计。

结果

符合寡转移标准(孤立性且符合正常标准)的患者生存率为53%。乳腺癌最为常见,生存率超过70%。患者的平均年龄为58岁。

讨论

癌症治疗中的全身治疗已成功改善无病生存曲线,并促使我们重新审视寡转移的治疗模式,即治疗应在肉瘤治疗专家中心进行。

结论

对于严格意义上(孤立性)且符合正常标准的寡转移患者,手术治疗的选择应由多学科团队根据患者的预后、肿瘤的解剖位置和组织类型进行评估。

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