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足月新生儿血浆醛固酮和11-脱氧皮质醇:一项重新评估。

Plasma aldosterone and 11-deoxycortisol in term neonates: a reevaluation.

作者信息

Dörr H G, Sippell W G, Versmold H T, Bidlingmaier F, Knorr D

出版信息

J Clin Endocrinol Metab. 1987 Jul;65(1):208-10. doi: 10.1210/jcem-65-1-208.

DOI:10.1210/jcem-65-1-208
PMID:3584398
Abstract

We reported previously reference values for seven corticosteroids in the plasma of term neonates and their mothers, including values for aldosterone (Aldo) that appeared high compared to the values in the literature. Plasma 11-deoxycortisol (S) was not measured in that longitudinal study. Using an improved technique of chromatographic separation of Aldo and S, the Aldo levels were measured again, and S levels were newly determined in stored plasma samples of the 12 newborn infants of our original report. The mean concentrations were: (Formula: see text). These plasma Aldo values should replace those of our original report. Thus, both plasma Aldo and S levels decline in the first week of life in normal infants.

摘要

我们之前报告了足月新生儿及其母亲血浆中七种皮质类固醇的参考值,其中醛固酮(Aldo)的值与文献中的值相比显得较高。在该项纵向研究中未测定血浆11-脱氧皮质醇(S)。采用改进的Aldo和S色谱分离技术,再次测定了Aldo水平,并在我们原始报告的12名新生儿的储存血浆样本中首次测定了S水平。平均浓度为:(公式:见正文)。这些血浆Aldo值应取代我们原始报告中的值。因此,正常婴儿出生后第一周血浆Aldo和S水平均下降。

相似文献

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Plasma aldosterone and 11-deoxycortisol in term neonates: a reevaluation.足月新生儿血浆醛固酮和11-脱氧皮质醇:一项重新评估。
J Clin Endocrinol Metab. 1987 Jul;65(1):208-10. doi: 10.1210/jcem-65-1-208.
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J Endocrinol Invest. 2011 Sep;34(8):604-8. doi: 10.3275/7330. Epub 2010 Nov 8.
2
Serum cortisol and cortisone levels in newborns with congenital adrenal hyperplasia before the start of therapy.先天性肾上腺增生症新生儿在开始治疗前的血清皮质醇和可的松水平。
J Endocrinol Invest. 2005 May;28(5):413-6. doi: 10.1007/BF03347220.
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Plasma aldosterone levels in the 1st week of life in infants of less than 30 weeks gestation.
孕周小于30周的婴儿出生后第1周的血浆醛固酮水平。
Eur J Pediatr. 2005 Mar;164(3):141-5. doi: 10.1007/s00431-004-1572-0. Epub 2004 Nov 19.