Dörr H G, Sippell W G, Versmold H T, Bidlingmaier F, Knorr D
J Clin Endocrinol Metab. 1987 Jul;65(1):208-10. doi: 10.1210/jcem-65-1-208.
We reported previously reference values for seven corticosteroids in the plasma of term neonates and their mothers, including values for aldosterone (Aldo) that appeared high compared to the values in the literature. Plasma 11-deoxycortisol (S) was not measured in that longitudinal study. Using an improved technique of chromatographic separation of Aldo and S, the Aldo levels were measured again, and S levels were newly determined in stored plasma samples of the 12 newborn infants of our original report. The mean concentrations were: (Formula: see text). These plasma Aldo values should replace those of our original report. Thus, both plasma Aldo and S levels decline in the first week of life in normal infants.
我们之前报告了足月新生儿及其母亲血浆中七种皮质类固醇的参考值,其中醛固酮(Aldo)的值与文献中的值相比显得较高。在该项纵向研究中未测定血浆11-脱氧皮质醇(S)。采用改进的Aldo和S色谱分离技术,再次测定了Aldo水平,并在我们原始报告的12名新生儿的储存血浆样本中首次测定了S水平。平均浓度为:(公式:见正文)。这些血浆Aldo值应取代我们原始报告中的值。因此,正常婴儿出生后第一周血浆Aldo和S水平均下降。