Editorial: Mechanisms of Action in Neurodegenerative Proteinopathies.
作者信息
Miller Sean J, Wray Selina, Sattler Rita, Zhang Can
机构信息
Pluripotent Diagnostics Corporation (PDx), Molecular Medicine Research Institute, Sunnyvale, CA, United States.
Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.
出版信息
Front Neurosci. 2022 Jun 30;16:968994. doi: 10.3389/fnins.2022.968994. eCollection 2022.
Abstract
摘要
相似文献
1
Editorial: Mechanisms of Action in Neurodegenerative Proteinopathies.社论：神经退行性蛋白质病的作用机制
Front Neurosci. 2022 Jun 30;16:968994. doi: 10.3389/fnins.2022.968994. eCollection 2022.
2
TDP-43 proteinopathies: pathological identification of brain regions differentiating clinical phenotypes.TDP-43 蛋白病：区分临床表型的大脑区域的病理学鉴定。
Brain. 2015 Oct;138(Pt 10):3110-22. doi: 10.1093/brain/awv220. Epub 2015 Jul 31.
3
Protein synthesis modulation as a therapeutic approach for amyotrophic lateral sclerosis and frontotemporal dementia.蛋白质合成调节作为肌萎缩侧索硬化症和额颞叶痴呆的一种治疗方法。
Neural Regen Res. 2022 Jul;17(7):1423-1430. doi: 10.4103/1673-5374.330593.
4
The role of transactive response DNA-binding protein-43 in amyotrophic lateral sclerosis and frontotemporal dementia.反式激活反应DNA结合蛋白43在肌萎缩侧索硬化症和额颞叶痴呆中的作用。
Curr Opin Neurol. 2008 Dec;21(6):693-700. doi: 10.1097/WCO.0b013e3283168d1d.
5
Biomarker discovery and development for frontotemporal dementia and amyotrophic lateral sclerosis.额颞叶痴呆和肌萎缩侧索硬化的生物标志物发现与开发
Brain. 2022 Jun 3;145(5):1598-1609. doi: 10.1093/brain/awac077.
6
Proteinopathies associated to repeat expansion disorders.与重复扩展障碍相关的蛋白构象病。
J Neural Transm (Vienna). 2022 Feb;129(2):173-185. doi: 10.1007/s00702-021-02454-5. Epub 2022 Jan 24.
7
Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration.系统综述和人类转录组学的荟萃分析揭示了神经炎症、能量代谢缺陷和蛋白质稳态失效在神经退行性变中的作用。
Neurobiol Dis. 2021 Feb;149:105225. doi: 10.1016/j.nbd.2020.105225. Epub 2020 Dec 19.
8
Degeneration of the locus coeruleus is a common feature of tauopathies and distinct from TDP-43 proteinopathies in the frontotemporal lobar degeneration spectrum.蓝斑核退化是tau 病的一个常见特征，与额颞叶变性谱中的 TDP-43 蛋白病不同。
Acta Neuropathol. 2020 Nov;140(5):675-693. doi: 10.1007/s00401-020-02210-1. Epub 2020 Aug 17.
9
Stathmin-2: adding another piece to the puzzle of TDP-43 proteinopathies and neurodegeneration.Stathmin-2：为 TDP-43 蛋白病和神经退行性变的谜题再添一块。
J Clin Invest. 2020 Nov 2;130(11):5677-5680. doi: 10.1172/JCI142854.
10
Clinical and pathological features of familial frontotemporal dementia caused by C9ORF72 mutation on chromosome 9p.9p 染色体上 C9ORF72 突变引起的家族性额颞叶痴呆的临床和病理特征。
Brain. 2012 Mar;135(Pt 3):709-22. doi: 10.1093/brain/awr354. Epub 2012 Feb 17.
引用本文的文献
1
Lysosomal targeting of liposomes with acidic pH and Cathepsin B induces protein aggregate clearance.具有酸性pH值和组织蛋白酶B的脂质体的溶酶体靶向作用可诱导蛋白质聚集体清除。
Cell Commun Signal. 2025 Jun 19;23(1):296. doi: 10.1186/s12964-025-02310-z.
2
Recent Advances in High-Content Imaging and Analysis in iPSC-Based Modelling of Neurodegenerative Diseases.基于 iPSC 的神经退行性疾病建模的高内涵成像和分析的最新进展。
Int J Mol Sci. 2023 Sep 28;24(19):14689. doi: 10.3390/ijms241914689.
3
The Effects of Galactic Cosmic Rays on the Central Nervous System: From Negative to Unexpectedly Positive Effects That Astronauts May Encounter.银河系宇宙射线对中枢神经系统的影响：从对宇航员可能产生的负面影响到意想不到的积极影响。
Biology (Basel). 2023 Mar 3;12(3):400. doi: 10.3390/biology12030400.
Zotero 插件