Suppr超能文献

肝动脉化疗栓塞术后原发性肝癌破裂出血行肝部分切除术的近期及远期疗效

Short-Term and Long-Term Curative Effect of Partial Hepatectomy on Ruptured Hemorrhage of Primary Liver Cancer after TAE.

作者信息

Xiao Xiulin, Zhou Lin, Zhang Long, Xu Zhiyuan, Dai Qixin, Deng Xiaohong

机构信息

Department of Hepatopancreatobiliary Surgery, Ganzhou People's Hospital, Ganzhou, Jiangxi 341000, China.

出版信息

Emerg Med Int. 2022 Jul 5;2022:2484418. doi: 10.1155/2022/2484418. eCollection 2022.

Abstract

OBJECTIVE

To observe the short-term and long-term curative effects of partial hepatectomy on ruptured hemorrhage of primary liver cancer after transcatheter arterial embolization (TAE).

METHODS

A total of 150 patients with primary liver cancer treated in the hospital were enrolled as research objects between February 2018 and February 2021, including 75 cases undergoing TAE in the TAE group and the other 75 cases undergoing elective partial hepatectomy after TAE in the combination group. The surgical related indexes (leaving bed time, discharge time, success rate of hemostasis, lesion clearance rate), mean arterial pressure (MAP), heart rate (HR), hemoglobin, and liver function indexes (serum alpha-fetoprotein (AFP), albumin (ALB), total bilirubin (TBIL)) before and after treatment, postoperative complications, survival rate, and recurrence rate at 1 year after surgery between the two groups were compared.

RESULTS

Compared with the TAE group, hospitalization time was shorter ( < 0.05), the success rate of hemostasis and lesions clearance rate were higher in the combination group ( < 0.05). After surgery, levels of HR and serum AFP were significantly decreased, while levels of MAP, hemoglobin, serum ALB, and TBIL were significantly increased in both groups. The levels of HR and serum AFP in the combination group were lower than those in the TAE group, while levels of MAP, hemoglobin, serum ALB, and TBIL were higher than those in the TAE group ( < 0.05). There was no significant difference in the incidence of postoperative complications between the two groups ( < 0.05). Compared with the TAE group, the recurrence rate was lower, and the survival rate was higher in the combination group at 1 year after surgery ( < 0.05).

CONCLUSION

Partial hepatectomy can effectively improve hemostatic effect and liver function in ruptured hemorrhage of primary liver cancer after TAE, increase survival rate, and reduce postoperative recurrence rate.

摘要

目的

观察部分肝切除术对经导管动脉栓塞术(TAE)后原发性肝癌破裂出血的近期及远期疗效。

方法

选取2018年2月至2021年2月在本院治疗的150例原发性肝癌患者作为研究对象,TAE组75例行TAE治疗,联合组75例行TAE后择期部分肝切除术。比较两组手术相关指标(下床时间、出院时间、止血成功率、病灶清除率)、治疗前后平均动脉压(MAP)、心率(HR)、血红蛋白及肝功能指标(血清甲胎蛋白(AFP)、白蛋白(ALB)、总胆红素(TBIL))、术后并发症、生存率及术后1年复发率。

结果

与TAE组比较,联合组住院时间缩短(<0.05),止血成功率及病灶清除率更高(<0.05)。术后两组HR及血清AFP水平均显著降低,MAP、血红蛋白、血清ALB及TBIL水平均显著升高。联合组HR及血清AFP水平低于TAE组,MAP、血红蛋白、血清ALB及TBIL水平高于TAE组(<0.05)。两组术后并发症发生率比较差异无统计学意义(<0.05)。与TAE组比较,联合组术后1年复发率更低,生存率更高(<0.05)。

结论

部分肝切除术可有效提高TAE后原发性肝癌破裂出血的止血效果及肝功能,提高生存率,降低术后复发率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5762/9277167/54b99efa33e9/EMI2022-2484418.001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验