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先天性心脏病与牙周疾病——有关联吗?

Congenital Heart Diseases and Periodontal Diseases-Is There a Link?

作者信息

Rughwani Roshan R, Cholan Priyanka K, Victor Dhayanand J

机构信息

Department of Periodontics and Oral Implantology, SRM Dental College, Chennai, India.

出版信息

Front Cardiovasc Med. 2022 Jun 30;9:937480. doi: 10.3389/fcvm.2022.937480. eCollection 2022.

Abstract

An understanding in the field of periodontal medicine explains the fact that the oral cavity serves as a niche for numerous pathogenic microorganisms. When these microorganisms or their by-products disseminate to the various parts of the body, they are capable of triggering diseases characterized by an altered host immune-inflammatory response in the anatomically distinct organ. This mechanism is reported in the propagation of cardiovascular diseases with respect to periodontal medicine. Abundant amount of literature suggests an association between atherosclerotic cardiovascular disease and periodontal diseases. However, there is very less data available to highlight the association between periodontal disease and non-atherosclerotic cardiovascular disease, such as congenital anomalies of the heart. This review outlines the relationship between periodontal diseases and congenital heart diseases and also helps us understand whether the presence of periodontal disease can worsen the preexisting congenital cardiac disease.

摘要

牙周医学领域的一项认识解释了这样一个事实,即口腔是众多致病微生物的滋生地。当这些微生物或其副产品扩散到身体的各个部位时,它们能够引发疾病,其特征是在解剖学上不同的器官中宿主免疫炎症反应发生改变。关于牙周医学,这种机制在心血管疾病的传播中已有报道。大量文献表明动脉粥样硬化性心血管疾病与牙周疾病之间存在关联。然而,很少有数据能够突出牙周疾病与非动脉粥样硬化性心血管疾病(如先天性心脏异常)之间的关联。这篇综述概述了牙周疾病与先天性心脏病之间的关系,也有助于我们了解牙周疾病的存在是否会使已有的先天性心脏病恶化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a19/9279652/79e8b4ea7119/fcvm-09-937480-g001.jpg

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