补骨脂素紫外线A光疗法诱发的色素沉着斑：一例累及掌跖皮肤的病例

PUVA-induced pigmented macules: a case involving palmoplantar skin.

作者信息

Bruce D R, Berger T G

出版信息

J Am Acad Dermatol. 1987 May;16(5 Pt 2):1087-90. doi: 10.1016/s0190-9622(87)70140-6.

Abstract

A patient with palmoplantar psoriasis received a local treatment regimen of psoralens with long-wave ultraviolet A radiation (PUVA). After approximately 12 months of treatment, she developed hyperpigmented macules on her palms and soles. A biopsy showed changes consistent with PUVA-induced pigmented macules, as well as pronounced pigmentary incontinence. No cytologic atypia was noted. PUVA-induced pigmented macules should now be included in the differential diagnosis of palmoplantar hyperpigmented macules.

摘要

一名掌跖银屑病患者接受了补骨脂素联合长波紫外线A辐射（PUVA）的局部治疗方案。治疗约12个月后，她的手掌和脚底出现了色素沉着斑。活检显示的变化符合PUVA诱导的色素沉着斑，以及明显的色素失禁。未发现细胞学异型性。现在，PUVA诱导的色素沉着斑应纳入掌跖色素沉着斑的鉴别诊断。