Conservative Dentistry and Endodontics, Gajanan Clinic, Kolkata, 700025 West Bengal, India.
Department of Conservative Dentistry and Endodontics, SRM Dental College, Ramapuram, 600089 Chennai, India.
Biomed Res Int. 2022 Jul 8;2022:3569281. doi: 10.1155/2022/3569281. eCollection 2022.
The healing of the periapical tissues is crucial to the success of root canal treatment. The review studies effectively examine various endodontic root canal sealants in terms of periapical healing. This systematic review was formulated following the PRISMA 2020 guidelines and registered in the international prospective register of systematic reviews (PROSPERO) number-CRD42021239192. To find relevant articles, PubMed Central and Medline databases (until February 2022) were searched. Studies that evaluated healing following the application of different endodontic sealers were analysed. A primary outcome measure was the resolution of periapical lesions following the endodontic treatment. In vivo studies comparing radiographic treatment outcomes and articles with a minimum of 6-month follow-up were included. A total of 9 clinical trial studies that met all the inclusion criteria were included in the analysis. The overall risk of bias was high in four studies out of nine studies. Periapical lesions showed significant healing after endodontic treatment regardless of sealer type, although bioceramic and bioactive sealers had shown better results.
根尖周组织的愈合对于根管治疗的成功至关重要。这些综述研究从根尖周愈合的角度有效地评估了各种根管封闭剂。本系统评价按照 PRISMA 2020 指南制定，并在国际前瞻性系统评价注册处（PROSPERO）进行了登记，编号为-CRD42021239192。为了找到相关文章，检索了 PubMed Central 和 Medline 数据库（截至 2022 年 2 月）。分析了评估不同根管封闭剂应用后愈合情况的研究。主要结局指标是根管治疗后根尖病变的消退情况。纳入了比较影像学治疗结果和至少 6 个月随访的体内研究。共有 9 项临床试验研究符合所有纳入标准。9 项研究中有 4 项研究的总体偏倚风险较高。无论封闭剂类型如何，根管治疗后根尖周病变均显示出明显的愈合，但生物陶瓷和生物活性封闭剂的效果更好。
