Kaba Riyaz A, Ahmed Omar, Behr Elijah, Momin Aziz
Cardiovascular Clinical Academic Group, Molecular and Clinical Sciences Institute, St George's, University of London and St George's University Hospitals NHS Foundation Trust, London, UK.
Department of Cardiology, Ashford and St Peter's NHS Foundation Trust, Chertsey, Surrey, UK.
Arrhythm Electrophysiol Rev. 2022 Apr;11:e12. doi: 10.15420/aer.2022.05.
The burden of AF is increasing in prevalence and healthcare resource usage in the UK and worldwide. It can result in impaired quality of life for affected patients, as well as increased risk of stroke, heart failure and mortality. A holistic, integrated approach to AF management is recommended, which may include a focus on reducing risk factors and on medical management with anticoagulation and anti-arrhythmic drugs. There are also various ablation strategies that may be considered when anti-arrhythmic drugs fail to alleviate symptoms and reduce AF burden. These ablation techniques range from standalone percutaneous endocardial catheter ablation to open surgical ablation procedures concomitant with cardiac surgery. More recently, hybrid ablation that combines aspects of both surgical and electrophysiologically targeted ablation has been described. This article reviews the evolution of ablation strategies, beginning with the origin of the Cox maze IV procedure and continuing to the recent hybrid convergent approach, and provides a summary of the associated outcomes.
在英国及全球范围内,房颤的负担在患病率和医疗资源使用方面都在增加。它会导致受影响患者的生活质量受损,以及中风、心力衰竭和死亡风险增加。建议采用全面、综合的房颤管理方法,这可能包括注重降低风险因素以及使用抗凝药和抗心律失常药物进行药物治疗。当抗心律失常药物无法缓解症状和减轻房颤负担时,也可考虑各种消融策略。这些消融技术范围从单独的经皮心内膜导管消融到与心脏手术同时进行的开放性外科消融手术。最近,已经描述了结合外科和电生理靶向消融两方面的杂交消融。本文回顾了消融策略的演变,从考克斯迷宫IV手术的起源开始,一直到最近的杂交融合方法,并总结了相关结果。