Neerhut Thomas, Ninan John, Crozier Jack, Lawson Malcolm, Rhee Handoo
Princess Alexandra Hospital, Brisbane, 199 Ipswich Road, Woolloongabba, 4102, Australia.
Princess Alexandra Hospital, Brisbane, Australia.
Urol Case Rep. 2022 Jul 8;44:102157. doi: 10.1016/j.eucr.2022.102157. eCollection 2022 Sep.
Few cases of Hypervirulent Klebsiella Pneumonia (HvKP) have been described. Even fewer cases with renal abscess and metastatic pulmonary spread are reported. Typically, prompt introduction of intravenous antibiotics leads to clinical resolution and more invasive measures of source control are rarely required. To date only one other case of disseminated metastatic HvKP requiring nephrectomy for infective source control is described. Here we present a rare case of metastatic HvKP refractory to intravenous antimicrobial therapy in an immunocompromised newly diagnosed diabetic patient. Specifically, we seek to illustrate the rapid effectiveness of surgical intervention following a poor response to initial treatment.
高毒力肺炎克雷伯菌（HvKP）感染的病例鲜有报道。肾脓肿并伴有肺转移的病例更是少见。通常，及时使用静脉抗生素治疗可使病情得到临床缓解，很少需要采取更具侵入性的源头控制措施。迄今为止，仅有另一例播散性转移性HvKP病例报道，该病例为控制感染源需要进行肾切除术。在此，我们报告一例免疫功能低下的新诊断糖尿病患者，其转移性HvKP对静脉抗菌治疗无效。具体而言，我们旨在说明在初始治疗效果不佳后手术干预的快速有效性。
