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阻塞性睡眠呼吸暂停患者精神疾病的患病率——一项来自印度克什米尔地区的横断面研究。

Prevalence of mental illness in patients with obstructive sleep apnea - A cross-sectional study from Kashmir, India.

作者信息

Shoib Sheikh, Ullah Irfan, Nagendrappa Sachin, Taseer Anab Rehan, De Berardis Domenico, Singh Manjeet, Asghar Muhammad Sohaib

机构信息

Department of Psychiatry, Jawahar Lal Nehru Memorial Hospital (JLNMH), Rainawari, Srinagar, Jammu and Kashmir, 190003, India.

Kabir Medical College, Gandhara University, Peshawar, Pakistan.

出版信息

Ann Med Surg (Lond). 2022 Jul 6;80:104056. doi: 10.1016/j.amsu.2022.104056. eCollection 2022 Aug.

Abstract

AIM

The study aimed to evaluate the prevalence of mental illness in obstructive sleep apnea (OSA) and to examine whether patients with obstructive sleep apnea require screening for mental illness.

METHODS

We performed polysomnography studies of patients that were referred from various subspecialty clinics in Kashmir from Jan 2020-December 2020. using the Mini-International Neuropsychiatric Interview (MINI plus) scale to make a psychiatric diagnosis. We administered the General Health Questionnaire - 28 (GHQ - 28), Hamilton Depression Rating Scale (HAM-D), and Hamilton Anxiety Rating Scale (HAM-A) to patients. Descriptive statistics and correlations were used for data analysis.

RESULTS

182 patients underwent polysomnography, 85 (46.7%) of which were suffering from mental illness Based on the Apnea-Hypopnea Index score, 8 (4.39%) patients had mild, 35 (41.1%) had moderate and 42 (49.4%) had severe OSA. The mean GHQ -28 score was significantly higher in patients with Obstructive sleep apnea (p < 0.001) (11.34 ± 8.2) as compared to non-Obstructive sleep apnea patients (1.98 ± 4.38).

CONCLUSIONS

This study demonstrates the increased prevalence of anxiety and depression in patients with OSA. Therefore, we recommend timely screening for any mental health issues in patients with OSA and necessary interventions to address the issues, thus preventing mental health morbidities in patients with OSA this would help subsequently in an improved lifestyle.

摘要

目的

本研究旨在评估阻塞性睡眠呼吸暂停(OSA)患者中精神疾病的患病率,并探讨阻塞性睡眠呼吸暂停患者是否需要进行精神疾病筛查。

方法

我们对2020年1月至2020年12月期间从克什米尔各专科门诊转诊的患者进行了多导睡眠图研究。使用迷你国际神经精神病学访谈(MINI plus)量表进行精神疾病诊断。我们对患者进行了一般健康问卷-28(GHQ-28)、汉密尔顿抑郁量表(HAM-D)和汉密尔顿焦虑量表(HAM-A)评估。采用描述性统计和相关性分析进行数据分析。

结果

182例患者接受了多导睡眠图检查,其中85例(占46.7%)患有精神疾病。根据呼吸暂停低通气指数评分,8例(占4.39%)患者为轻度阻塞性睡眠呼吸暂停,35例(占41.1%)为中度,42例(占49.4%)为重度。阻塞性睡眠呼吸暂停患者的平均GHQ-28评分(11.34±8.2)显著高于非阻塞性睡眠呼吸暂停患者(1.98±4.38)(p<0.001)。

结论

本研究表明阻塞性睡眠呼吸暂停患者焦虑和抑郁的患病率增加。因此,我们建议对阻塞性睡眠呼吸暂停患者及时筛查任何心理健康问题,并采取必要的干预措施来解决这些问题,从而预防阻塞性睡眠呼吸暂停患者的心理健康疾病,这随后将有助于改善生活方式。

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Obstructive sleep apnoea and schizophrenia--a research agenda.阻塞性睡眠呼吸暂停与精神分裂症——研究议程。
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