Shoib Sheikh, Malik Javid A, Masoodi Shariq
Department of Health, JK Health Services, Srinagar, Jammu and Kashmir, India.
Department of Chest Medicine, SKIMS Medical College, Srinagar, Jammu and Kashmir, India.
Ind Psychiatry J. 2017 Jul-Dec;26(2):183-187. doi: 10.4103/ipj.ipj_78_16.
Obstructive sleep apnea (OSA) often results in a wide range of psychological symptoms. The relationship of depressive disorders and depressive symptoms with body mass index (BMI) and severity of sleep apnea were the subject of numerous studies; results, however, were inconclusive in the majority of studies. Keeping this in view, we studied the correlates of depressive symptoms in patients with OSA. Relationships between BMI and depressive symptoms in patients with OSA.
We performed polysomnography (PSG) studies of patients that were referred from various subspecialty clinics from July 2011 to August 2013. Ninety-five women and 87 men (total 182) diagnosed with OSA were reviewed for the presence of depressive symptoms and degree of sleepiness using the Epworth Sleepiness Scale (ESS) scores Hamilton Depression Rating Scale (HAM-D). Moreover, Mini-International Neuropsychiatric Interview Scale was applied at the time of PSG. This was followed by application of standard methods of statistical analysis.
Our sample included 27 (42.6%) men and 20 (57.4%) women, with a mean age of 58.60 ± 14.75 years. Women (61.6 ± 10.0) had a mean age significantly more ( = 0.011) than that of men (54.0 ± 13.0). BMI has a statistical significant correlation with apnea-hypopnea index (correlation is significant at the 0.05 level [two-tailed]), ESS (correlation is significant at the 0.05 level [two-tailed]), and HAM-D (correlation is significant at the 0.01 level [two-tailed]).
Depressive symptoms are more common and more severe in women with OSA than in men. There is definite relationship between BMI and depressive symptoms in patients with OSA. There is no causal relationship between OSA and depressive symptoms in the population studied.
阻塞性睡眠呼吸暂停（OSA）常导致多种心理症状。抑郁症及抑郁症状与体重指数（BMI）和睡眠呼吸暂停严重程度之间的关系是众多研究的主题；然而，大多数研究结果尚无定论。鉴于此，我们研究了阻塞性睡眠呼吸暂停患者抑郁症状的相关因素。阻塞性睡眠呼吸暂停患者BMI与抑郁症状之间的关系。
我们对2011年7月至2013年8月从各个专科门诊转诊的患者进行了多导睡眠图（PSG）研究。对95名女性和87名男性（共182名）被诊断为阻塞性睡眠呼吸暂停的患者，使用爱泼沃斯思睡量表（ESS）评分、汉密尔顿抑郁量表（HAM-D）评估抑郁症状的存在情况和嗜睡程度。此外，在进行PSG检查时应用了迷你国际神经精神访谈量表。随后采用标准的统计分析方法。
我们的样本包括27名（42.6%）男性和20名（57.4%）女性，平均年龄为58.60±14.75岁。女性（61.6±10.0）的平均年龄显著高于男性（54.0±13.0）（P = 0.011）。BMI与呼吸暂停低通气指数（在0.05水平[双侧]相关性显著）、ESS（在0.05水平[双侧]相关性显著）和HAM-D（在0.01水平[双侧]相关性显著）具有统计学显著相关性。
阻塞性睡眠呼吸暂停女性患者的抑郁症状比男性更常见、更严重。阻塞性睡眠呼吸暂停患者的BMI与抑郁症状之间存在明确关系。在所研究的人群中，阻塞性睡眠呼吸暂停与抑郁症状之间不存在因果关系。
